Multi-Scale Modeling of HIV Infection in vitro and APOBEC3G-Based Anti-Retroviral Therapy
Figure 2
Time-dependent profile of virus release from a single cell.
The time evolution of total number of A3G(−) and A3G(+) viruses produced inside a single cell and released from it is shown. Infection occurs at t = 0. Production of new viruses begins approximately 16 hours after infection. Light and dark green colors represent A3G(−) and A3G(+) viruses inside the cell. Newly produced viruses get released to the extracellular environment at 22 hours post infection and the virus release continues until the cell dies approximately 55 hours after infection. A3G(−) and A3G(+) viruses outside the cell are represented by light and dark brown colors.