Temporal Encoding in a Nervous System
Figure 9
iSTAC analysis of data-based and synthetic models.
A: Mean of data-based (red) and synthetic (purple) multivariate Gaussian models for stimulus preceding a 2 ms doublet, from the same cell as in Figures 7A and 7B. Covariance of data-based and synthetic models are shown in panels B and C, respectively (color scale in mm2/sec2). D: Estimate of the 3 most informative iSTAC dimensions (shaded area indicates mean ± SD across 10× validation). E: Measure of the total normalized K-L divergence between data-based and synthetic models for 2, 5, and 8 ms, as a function of subspace dimensionality. Mean ± SD across 10× validation is shown with error bars, which are on the order of the size of the markers for the points. F: Measure of the portion of the total K-L divergence explained by the subspace containing the three largest iSTAC vectors, as a function of ISI in the model. G: Improvement of the synthetic model performance in LLR tests from the single cell in Figure 7B (black markers) by modification along the 3-dimensional subspace shown in panel 9D (cyan markers). Error bars represent ±95% CIs on the mean.