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Wide-Field Motion Integration in Fly VS Cells: Insights from an Inverse Approach

Figure 7

Comparison of the intrinsic dynamics of the reference model and optimized models.

Intrinsic physiology is here determined in a current-clamp simulation. Injected currents are (in steps of 1) from to nA in the reference model (A) and from to nA in the optimized models (B: passive model, C: active mode). The optimized models show the same qualitative dynamics as the reference model: (i) outward rectification, (ii) a dampening oscillation after injection, and (iii) strong after-depolarization. Note that the dynamics are not optimized explicitly but emergent, corroborating the hypothesis of wide-field motion integration in VS cells. B: *In the passive model, active conductances were inserted as in the reference model, after optimization with passive properties only.

Figure 7

doi: https://doi.org/10.1371/journal.pcbi.1000932.g007