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Dissimilatory Metabolism of Nitrogen Oxides in Bacteria: Comparative Reconstruction of Transcriptional Networks

Figure 10

Regulatory Interactions between Genes for Dissimilatory Nitrogen Oxides Metabolism in Bacteria

(A) Distribution of regulators and regulated genes. The number of cases when a gene is regulated by a specific transcription factor is indicated by the length of a colored bar in the histogram. The white bar in the histogram shows the cases when the gene is present in a genome possessing at least one of the studied regulons, but is not regulated by any of them.

(B) Combined regulatory network. Arrows denote regulatory interactions, with the thickness reflecting the frequency of the interaction in the analyzed genomes. Experimentally established (for DNR, NnrR, NsrR, and NorR) and predicted based on the regulon content (for HcpR) signal molecules are shown in filled ovals, and the protein family for each transcription factor is shown below.

Figure 10

doi: https://doi.org/10.1371/journal.pcbi.0010055.g010