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Open Access
Peer-reviewed
Research Article
Cellular morphodynamics as quantifiers for functional states of resident tissue macrophages in vivo
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Miriam Schnitzerlein ,
Contributed equally to this work with: Miriam Schnitzerlein, Eric Greto
Roles Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliations Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, Max-Planck-Zentrum für Physik und Medizin, Erlangen, Germany, Max Planck Institute for the Science of Light, Erlangen, Germany
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Eric Greto ,
Contributed equally to this work with: Miriam Schnitzerlein, Eric Greto
Roles Data curation, Formal analysis, Investigation, Software, Validation, Writing – review & editing
Affiliations Department of Medicine 3 - Rheumatology and Immunology, FAU and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie, FAU, Erlangen, Germany, Exploratory Research Unit, Optical Imaging Competence Center Erlangen, FAU, Erlangen, Germany
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Anja Wegner,
Roles Data curation, Investigation, Validation, Writing – review & editing
Affiliations Department of Medicine 3 - Rheumatology and Immunology, FAU and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie, FAU, Erlangen, Germany, Exploratory Research Unit, Optical Imaging Competence Center Erlangen, FAU, Erlangen, Germany
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Anna Möller,
Roles Data curation, Software, Validation
Affiliations Department of Medicine 3 - Rheumatology and Immunology, FAU and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie, FAU, Erlangen, Germany, Exploratory Research Unit, Optical Imaging Competence Center Erlangen, FAU, Erlangen, Germany, Department of Artificial Intelligence in Biomedical Engineering, FAU, Erlangen, Germany
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Oliver Aust,
Roles Software
Affiliations Department of Medicine 3 - Rheumatology and Immunology, FAU and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie, FAU, Erlangen, Germany, Exploratory Research Unit, Optical Imaging Competence Center Erlangen, FAU, Erlangen, Germany, Department of Artificial Intelligence in Biomedical Engineering, FAU, Erlangen, Germany
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Oumaima Ben Brahim,
Roles Data curation, Investigation
Affiliations Department of Medicine 3 - Rheumatology and Immunology, FAU and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie, FAU, Erlangen, Germany, Exploratory Research Unit, Optical Imaging Competence Center Erlangen, FAU, Erlangen, Germany
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David B. Blumenthal,
Roles Software, Supervision, Validation
Affiliation Department of Artificial Intelligence in Biomedical Engineering, FAU, Erlangen, Germany
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Vasily Zaburdaev ,
Roles Conceptualization, Supervision, Validation, Writing – review & editing
* E-mail: stefan.uderhardt@fau.de (SU); vasily.zaburdaev@fau.de (VZ)
¶‡ These authors contributed equally as corresponding authors.
Affiliations Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany, Max-Planck-Zentrum für Physik und Medizin, Erlangen, Germany
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Stefan Uderhardt
Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – review & editing
* E-mail: stefan.uderhardt@fau.de (SU); vasily.zaburdaev@fau.de (VZ)
¶‡ These authors contributed equally as corresponding authors.
Affiliations Department of Medicine 3 - Rheumatology and Immunology, FAU and Universitätsklinikum Erlangen, Erlangen, Germany, Deutsches Zentrum für Immuntherapie, FAU, Erlangen, Germany, Exploratory Research Unit, Optical Imaging Competence Center Erlangen, FAU, Erlangen, Germany
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Cellular morphodynamics as quantifiers for functional states of resident tissue macrophages in vivo
- Miriam Schnitzerlein,
- Eric Greto,
- Anja Wegner,
- Anna Möller,
- Oliver Aust,
- Oumaima Ben Brahim,
- David B. Blumenthal,
- Vasily Zaburdaev,
- Stefan Uderhardt
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- Published: May 29, 2025
- https://doi.org/10.1371/journal.pcbi.1011859