Contact-number-driven virus evolution: A multi-level modeling framework for the evolution of acute or persistent RNA virus infection

• Junya Sunagawa ,

  Contributed equally to this work with: Junya Sunagawa, Ryo Komorizono, Hyeongki Park

  Roles Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Advanced Transdisciplinary Science, Hokkaido University, Sapporo, Hokkaido, Japan

  https://orcid.org/0000-0001-7608-4253

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• Ryo Komorizono ,

  Contributed equally to this work with: Junya Sunagawa, Ryo Komorizono, Hyeongki Park

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Laboratory of RNA Viruses, Department of Virus Research, Institute for Life and Medical Sciences (LiMe), Kyoto University, Kyoto, Japan

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• Hyeongki Park ,

  Contributed equally to this work with: Junya Sunagawa, Ryo Komorizono, Hyeongki Park

  Roles Writing – original draft, Writing – review & editing

  Affiliation interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan

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• William S. Hart,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Mathematical Institute, University of Oxford, Oxford, United Kingdom

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• Robin N. Thompson,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliations Mathematics Institute, University of Warwick, Coventry, United Kingdom, Zeeman Institute for Systems Biology and Infectious Disease Epidemiology Research, University of Warwick, Coventry, United Kingdom

  https://orcid.org/0000-0001-8545-5212

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• Akiko Makino,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliations Laboratory of RNA Viruses, Department of Virus Research, Institute for Life and Medical Sciences (LiMe), Kyoto University, Kyoto, Japan, Laboratory of RNA Viruses, Graduate School of Biostudies, Kyoto University, Kyoto, Japan

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• Keizo Tomonaga ,

  Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing

  ¶‡ KT and SI also contributed equally to this work.

  Affiliations Laboratory of RNA Viruses, Department of Virus Research, Institute for Life and Medical Sciences (LiMe), Kyoto University, Kyoto, Japan, Laboratory of RNA Viruses, Graduate School of Biostudies, Kyoto University, Kyoto, Japan, Department of Molecular Virology, Graduate School of Medicine, Kyoto University, Kyoto, Japan

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• Shingo Iwami ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: iwami.iblab@bio.nagoya-u.ac.jp (SI); ryamaguchi@sci.hokudai.ac.jp (RY)

  ¶‡ KT and SI also contributed equally to this work.

  Affiliations interdisciplinary Biology Laboratory (iBLab), Division of Natural Science, Graduate School of Science, Nagoya University, Nagoya, Japan, Institute of Mathematics for Industry, Kyushu University, Fukuoka, Japan, Institute for the Advanced Study of Human Biology (ASHBi), Kyoto University, Kyoto, Japan, Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS), RIKEN, Saitama, Japan, NEXT-Ganken Program, Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan, Science Groove Inc., Fukuoka, Japan

  https://orcid.org/0000-0002-1780-350X

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• Ryo Yamaguchi

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: iwami.iblab@bio.nagoya-u.ac.jp (SI); ryamaguchi@sci.hokudai.ac.jp (RY)

  Affiliations Department of Advanced Transdisciplinary Science, Hokkaido University, Sapporo, Hokkaido, Japan, Department of Zoology & Biodiversity Research Centre, University of British Columbia, Vancouver, British Columbia, Canada

  https://orcid.org/0000-0003-3545-7513

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