Deconvolving the contributions of cell-type heterogeneity on cortical gene expression

• Ellis Patrick ,

  Contributed equally to this work with: Ellis Patrick, Mariko Taga, Ayla Ergun

  Roles Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia, The Westmead Institute for Medical Research, The University of Sydney, Sydney, New South Wales, Australia

  http://orcid.org/0000-0002-5253-4747

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• Mariko Taga ,

  Contributed equally to this work with: Ellis Patrick, Mariko Taga, Ayla Ergun

  Roles Data curation, Visualization, Writing – review & editing

  Affiliation Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York City, New York, United States of America

  ⨯
• Ayla Ergun ,

  Contributed equally to this work with: Ellis Patrick, Mariko Taga, Ayla Ergun

  Roles Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Research and Development, Biogen, Cambridge, Massachusetts, United States of America

  http://orcid.org/0000-0002-7934-1259

  ⨯
• Bernard Ng,

  Roles Visualization, Writing – original draft, Writing – review & editing

  Affiliations Departments of Statistics and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada, Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada

  http://orcid.org/0000-0002-8688-3873

  ⨯
• William Casazza,

  Roles Visualization

  Affiliations Departments of Statistics and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada, Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada, The Bioinformatics Training Program, University of British Columbia, Vancouver, Canada

  http://orcid.org/0000-0002-4636-4710

  ⨯
• Maria Cimpean,

  Roles Resources

  Affiliation Department of Pediatrics, Division of Rheumatology, Washington University School of Medicine, St. Louis, Missouri, United States of America

  http://orcid.org/0000-0003-3735-2643

  ⨯
• Christina Yung,

  Roles Data curation

  Affiliation Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York City, New York, United States of America

  ⨯
• Julie A. Schneider,

  Roles Resources, Writing – review & editing

  Affiliation Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America

  ⨯
• David A. Bennett,

  Roles Resources, Writing – review & editing

  Affiliation Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America

  ⨯
• Chris Gaiteri,

  Roles Resources, Writing – review & editing

  Affiliation Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago, Illinois, United States of America

  ⨯
• Philip L. De Jager ,

  Roles Conceptualization, Funding acquisition, Resources, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work

  Affiliation Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York City, New York, United States of America

  http://orcid.org/0000-0002-8057-2505

  ⨯
• Elizabeth M. Bradshaw ,

  Roles Conceptualization, Resources, Supervision, Writing – review & editing

  ¶‡ These authors are joint senior authors on this work

  Affiliation Department of Neurology, Columbia University Medical Center, New York City, New York, United States of America

  http://orcid.org/0000-0002-6766-4325

  ⨯
• Sara Mostafavi

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: saram@stat.ubc.ca

  ¶‡ These authors are joint senior authors on this work

  Affiliations Departments of Statistics and Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada, Centre for Molecular Medicine and Therapeutics, Vancouver, British Columbia, Canada

  http://orcid.org/0000-0003-4698-1177

  ⨯