Correction of copy number induced false positives in CRISPR screens

Antoine de Weck; Javad Golji; Michael D. Jones; Joshua M. Korn; Eric Billy; E. Robert McDonald III; Tobias Schmelzle; Hans Bitter; Audrey Kauffmann

doi:10.1371/journal.pcbi.1006279

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Open Access

Peer-reviewed

Research Article

Correction of copy number induced false positives in CRISPR screens

Antoine de Weck ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

* E-mail: antoine.deweck@novartis.com (AW); audrey.kauffmann@novartis.com (AK)

Affiliation Novartis Institutes for Biomedical Research, Basel, Switzerland

http://orcid.org/0000-0003-0887-6771

⨯
Javad Golji,

Roles Data curation, Resources

Affiliation Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America
⨯
Michael D. Jones,

Roles Data curation, Resources

Affiliation Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America
⨯
Joshua M. Korn,

Roles Data curation, Resources

Affiliation Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America
⨯
Eric Billy,

Roles Conceptualization, Investigation, Resources

Affiliation Novartis Institutes for Biomedical Research, Basel, Switzerland

http://orcid.org/0000-0002-8859-0089

⨯
E. Robert McDonald III,

Roles Conceptualization, Investigation, Resources

Affiliation Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America
⨯
Tobias Schmelzle,

Roles Conceptualization, Resources

Affiliation Novartis Institutes for Biomedical Research, Basel, Switzerland
⨯
Hans Bitter,

Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

Affiliation Novartis Institutes for Biomedical Research, Cambridge, MA, United States of America
⨯
Audrey Kauffmann

Roles Conceptualization, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: antoine.deweck@novartis.com (AW); audrey.kauffmann@novartis.com (AK)

Affiliation Novartis Institutes for Biomedical Research, Basel, Switzerland
⨯

Correction of copy number induced false positives in CRISPR screens

Antoine de Weck,
Javad Golji,
Michael D. Jones,
Joshua M. Korn,
Eric Billy,
E. Robert McDonald III,
Tobias Schmelzle,
Hans Bitter,
Audrey Kauffmann

Published: July 19, 2018
https://doi.org/10.1371/journal.pcbi.1006279
See the preprint

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