Automated and Accurate Estimation of Gene Family Abundance from Shotgun Metagenomes

• Stephen Nayfach,

  Affiliation Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America

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• Patrick H. Bradley,

  Affiliation Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America

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• Stacia K. Wyman,

  Affiliation Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America

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• Timothy J. Laurent,

  Current Address: Invitae, San Francisco, California, United States of America

  Affiliation Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America

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• Alex Williams,

  Affiliation Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America

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• Jonathan A. Eisen,

  Affiliation Department of Evolution and Ecology, Department of Medical Microbiology and Immunology, UC Davis Genome Center, University of California, Davis, Davis, California, United States of America

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• Katherine S. Pollard ,

  * E-mail: kpollard@gladstone.ucsf.edu (KSP); thomas.sharpton@oregonstate.edu (TJS)

  Affiliations Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America, Department of Epidemiology and Biostatistics and Institute for Human Genetics, University of California, San Francisco, San Francisco, California, United States of America

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• Thomas J. Sharpton

  * E-mail: kpollard@gladstone.ucsf.edu (KSP); thomas.sharpton@oregonstate.edu (TJS)

  Affiliations Gladstone Institute of Cardiovascular Disease, San Francisco, California, United States of America, Department of Microbiology, Department of Statistics, Oregon State University, Corvallis, Oregon, United States of America

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