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Open Access
Peer-reviewed
Research Article
Characterizing Protein Interactions Employing a Genome-Wide siRNA Cellular Phenotyping Screen
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Apichat Suratanee,
Affiliation Department of Mathematics, Faculty of Applied Science, King Mongkut's University of Technology North Bangkok, Bangsue, Bangkok, Thailand
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Martin H. Schaefer,
Affiliation EMBL/CRG Systems Biology Research Unit, Center for Genomic Regulation, Barcelona, Spain
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Matthew J. Betts,
Affiliation Robert B. Russell, Cell Networks Protein Evolution, BioQuant, University of Heidelberg, Heidelberg, Germany
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Zita Soons,
Affiliations Network Modeling, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena, Jena, Germany, Department of Knowledge Engineering, Maastricht University, Maastricht, The Netherlands, Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany
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Heiko Mannsperger,
Affiliation Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany
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Nathalie Harder,
Affiliations Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany, Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, BioQuant, University of Heidelberg, Heidelberg, Germany
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Marcus Oswald,
Affiliations Network Modeling, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena, Jena, Germany, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany, Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany
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Markus Gipp,
Affiliation Department of Computer Science V, Institute of Computer Engineering, University of Mannheim, Mannheim, Germany
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Ellen Ramminger,
Affiliation AG Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Berlin, Germany
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Guillermo Marcus,
Affiliation Department of Computer Science V, Institute of Computer Engineering, University of Mannheim, Mannheim, Germany
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Reinhard Männer,
Affiliation Department of Computer Science V, Institute of Computer Engineering, University of Mannheim, Mannheim, Germany
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Karl Rohr,
Affiliations Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany, Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, BioQuant, University of Heidelberg, Heidelberg, Germany
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Erich Wanker,
Affiliation AG Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Berlin, Germany
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Robert B. Russell,
Affiliation Robert B. Russell, Cell Networks Protein Evolution, BioQuant, University of Heidelberg, Heidelberg, Germany
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Miguel A. Andrade-Navarro,
Affiliation Computational Biology and Data Mining Group, Max Delbrueck Center for Molecular Medicine, Berlin, Germany
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Roland Eils ,
* E-mail: r.eils@dkfz.de (RE); r.koenig@dkfz.de (RK)
Affiliations Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany, Department of Bioinformatics and Functional Genomics, Institute of Pharmacy and Molecular Biotechnology, BioQuant, University of Heidelberg, Heidelberg, Germany
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Rainer König
* E-mail: r.eils@dkfz.de (RE); r.koenig@dkfz.de (RK)
Affiliations Network Modeling, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena, Jena, Germany, Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany, Theoretical Bioinformatics, German Cancer Research Center, Heidelberg, Germany
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Characterizing Protein Interactions Employing a Genome-Wide siRNA Cellular Phenotyping Screen
- Apichat Suratanee,
- Martin H. Schaefer,
- Matthew J. Betts,
- Zita Soons,
- Heiko Mannsperger,
- Nathalie Harder,
- Marcus Oswald,
- Markus Gipp,
- Ellen Ramminger,
- Guillermo Marcus
- Published: September 25, 2014
- https://doi.org/10.1371/journal.pcbi.1003814