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hypergraphs are also useful for sequence alignment!

Posted by rbradley on 08 Jun 2009 at 16:16 GMT

I enjoyed your Perspective on hypergraphs for cellular biology. We published an article, "Fast Statistical Alignment," in this same issue where we use hypergraphs for a rather different application. We explicitly represent a multiple sequence alignment as a hypergraph (which can be described by a partially ordered set) and then dynamically construct the hypergraph using pairwise homology statements.

No competing interests declared.

RE: hypergraphs are also useful for sequence alignment!

PLOS_CompBiol replied to rbradley on 09 Jun 2009 at 09:33 GMT

You can find the article "Fast Statistical Alignment" here:
http://www.ploscompbiol.o...

No competing interests declared.