Quantification and Classification of E. coli Proteome Utilization and Unused Protein Costs across Environments

Edward J. O’Brien; Jose Utrilla; Bernhard O. Palsson

doi:10.1371/journal.pcbi.1004998

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Open Access

Peer-reviewed

Research Article

Quantification and Classification of E. coli Proteome Utilization and Unused Protein Costs across Environments

Edward J. O’Brien,

Affiliations Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America, Bioinformatics and Systems Biology program, University of California, San Diego, La Jolla, California, United States of America
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Jose Utrilla,

Affiliations Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America, Centro de Ciencias Genómicas. Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México
⨯
Bernhard O. Palsson

* E-mail: palsson@eng.ucsd.edu

Affiliations Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark, Department of Pediatrics, University of California, San Diego, La Jolla, California, United States of America
⨯

Quantification and Classification of E. coli Proteome Utilization and Unused Protein Costs across Environments

Edward J. O’Brien,
Jose Utrilla,
Bernhard O. Palsson

Published: June 28, 2016
https://doi.org/10.1371/journal.pcbi.1004998

About the Authors

Edward J. O’Brien

Affiliations Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America, Bioinformatics and Systems Biology program, University of California, San Diego, La Jolla, California, United States of America

Jose Utrilla

Affiliations Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America, Centro de Ciencias Genómicas. Universidad Nacional Autónoma de México, Cuernavaca, Morelos, México

Bernhard O. Palsson

* E-mail: palsson@eng.ucsd.edu

Affiliations Department of Bioengineering, University of California, San Diego, La Jolla, California, United States of America, Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Lyngby, Denmark, Department of Pediatrics, University of California, San Diego, La Jolla, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EJO BOP. Performed the experiments: EJO JU. Analyzed the data: EJO. Wrote the paper: EJO JU BOP.

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Proteomes
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Protein expression
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Glucose
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Transcriptome analysis
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Batch culture
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Proteomic databases
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C-reactive proteins
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Evolutionary rate
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