About the Authors

Andrew F. Neuwald


Affiliation Institute for Genome Sciences and Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Stephen F. Altschul

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AFN. Performed the experiments: AFN. Analyzed the data: AFN. Contributed reagents/materials/analysis tools: AFN SFA. Wrote the paper: AFN SFA. Designed and implemented routines for Dirichlet mixture priors and BILD scores: SFA. Designed and implemented other aspects of the GISMO program: AFN.