About the Authors

Yun-Ching Chen

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Christopher Douville

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Cheng Wang

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Noushin Niknafs

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Grace Yeo

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Violeta Beleva-Guthrie

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Hannah Carter

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Peter D. Stenson

Affiliation Institute of Medical Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom

David N. Cooper

Affiliation Institute of Medical Genetics, School of Medicine, Cardiff University, Heath Park, Cardiff, United Kingdom

Biao Li

Affiliation Buck Institute for Research on Aging, Novato, California, United States of America

Sean Mooney

Affiliation Buck Institute for Research on Aging, Novato, California, United States of America

Rachel Karchin

karchin@jhu.edu

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, The Johns Hopkins University, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YCC RK. Performed the experiments: YCC CD CW NN. Analyzed the data: YCC GY VBG. Contributed reagents/materials/analysis tools: HC PDS DNC BL SM. Contributed to the writing of the manuscript: YCC RK.