Simple Epidemiological Dynamics Explain Phylogenetic Clustering of HIV from Patients with Recent Infection

Erik M. Volz; James S. Koopman; Melissa J. Ward; Andrew Leigh Brown; Simon D. W. Frost

doi:10.1371/journal.pcbi.1002552

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Open Access

Peer-reviewed

Research Article

Simple Epidemiological Dynamics Explain Phylogenetic Clustering of HIV from Patients with Recent Infection

Erik M. Volz ,

* E-mail: erikvolz@umich.edu

Affiliation Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
James S. Koopman,

Affiliation Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Melissa J. Ward,

Affiliation Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
⨯
Andrew Leigh Brown,

Affiliation Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom
⨯
Simon D. W. Frost

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
⨯

Simple Epidemiological Dynamics Explain Phylogenetic Clustering of HIV from Patients with Recent Infection

Erik M. Volz,
James S. Koopman,
Melissa J. Ward,
Andrew Leigh Brown,
Simon D. W. Frost

Published: June 28, 2012
https://doi.org/10.1371/journal.pcbi.1002552

About the Authors

Erik M. Volz

* E-mail: erikvolz@umich.edu

Affiliation Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America

James S. Koopman

Affiliation Department of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of America

Melissa J. Ward

Affiliation Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

Andrew Leigh Brown

Affiliation Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, United Kingdom

Simon D. W. Frost

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EMV SDWF. Performed the experiments: EMV. Analyzed the data: EMV SDWF. Contributed reagents/materials/analysis tools: EMV SDWF. Wrote the paper: EMV JSK MJW ALB SDWF.

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Phylogenetics
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Epidemiological statistics
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HIV epidemiology
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Phylogenetic analysis
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HIV
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HIV infections
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HIV-1
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Population genetics
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