About the Authors

Yu Xia

yuxia@bu.edu

Affiliations Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America, Department of Chemistry, Boston University, Boston, Massachusetts, United States of America

Eric A. Franzosa

Affiliation Bioinformatics Program, Boston University, Boston, Massachusetts, United States of America

Mark B. Gerstein

Affiliation Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YX MBG. Performed the experiments: YX EAF. Analyzed the data: YX EAF. Wrote the paper: YX EAF.