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May 2008

Molecular zip codes for odor receptor gene choice in Drosophila. Scanning electron micrograph of a Drosophila head overlaid with expression patterns of four odor receptor genes in the antenna (blue, yellow, and magenta) and the maxillary palp (green). Sequences represent cis elements conserved upstream of odor receptor genes across 12 Drosophila species.

Image Credit: Design by Anandasankar Ray and Woodstock Tom; SEM by Jennifer Perry

Essay

Evolution and Creationism in America's Classrooms: A National Portrait

Michael B Berkman, Julianna Sandell Pacheco, Eric Plutzer

Unsolved Mystery

Sperm Sociality: Cooperation, Altruism, and Spite

Tommaso Pizzari, Kevin R Foster

Perspectives

The Challenge of Conserving Amphibian Megadiversity in Madagascar

Franco Andreone, Angus I Carpenter, Neil Cox, Louis du Preez, Karen Freeman, Samuel Furrer, Gerardo Garcia, Frank Glaw, Julian Glos, David Knox, Jörn Köhler, Joseph R Mendelson III, Vincenzo Mercurio, Russell A Mittermeier, Robin D Moore, Nirhy H. C Rabibisoa, Herilala Randriamahazo, Harison Randrianasolo, Noromalala Rasoamampionona Raminosoa, Olga Ravoahangimalala Ramilijaona, Christopher J Raxworthy, Denis Vallan, Miguel Vences, David R Vieites, Ché Weldon

Primer

Man versus Machine versus Ribozyme

Andrew D Ellington

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Resource Heterogeneity Moderates the Biodiversity-Function Relationship in Real World Ecosystems

Jason M Tylianakis, Tatyana A Rand, Ansgar Kahmen, Alexandra-Maria Klein, Nina Buchmann, Jörg Perner, Teja Tscharntke

Nongenetic Individuality in the Host–Phage Interaction

Sivan Pearl, Chana Gabay, Roy Kishony, Amos Oppenheim, Nathalie Q Balaban

Circadian Transcription Contributes to Core Period Determination in Drosophila

Sebastian Kadener, Jerome S Menet, Rebecca Schoer, Michael Rosbash

Genetic and Physiologic Dissection of the Vertebrate Cardiac Conduction System

Neil C Chi, Robin M Shaw, Benno Jungblut, Jan Huisken, Tania Ferrer, Rima Arnaout, Ian Scott, Dimitris Beis, Tong Xiao, Herwig Baier, Lily Y Jan, Martin Tristani-Firouzi, Didier Y. R Stainier

Mapping the Genetic Architecture of Gene Expression in Human Liver

Eric E Schadt, Cliona Molony, Eugene Chudin, Ke Hao, Xia Yang, Pek Y Lum, Andrew Kasarskis, Bin Zhang, Susanna Wang, Christine Suver, Jun Zhu, Joshua Millstein, Solveig Sieberts, John Lamb, Debraj GuhaThakurta, Jonathan Derry, John D Storey, Iliana Avila-Campillo, Mark J Kruger, Jason M Johnson, Carol A Rohl, Atila van Nas, Margarete Mehrabian, Thomas A Drake, Aldons J Lusis, Ryan C Smith, F. Peter Guengerich, Stephen C Strom, Erin Schuetz, Thomas H Rushmore, Roger Ulrich

Biogenesis of the Trypanosome Endo-Exocytotic Organelle Is Cytoskeleton Mediated

Mélanie Bonhivers, Sophie Nowacki, Nicolas Landrein, Derrick R Robinson

Topography of Thalamic Projections Requires Attractive and Repulsive Functions of Netrin-1 in the Ventral Telencephalon

Ashton W Powell, Takayuki Sassa, Yongqin Wu, Marc Tessier-Lavigne, Franck Polleux

A Regulatory Code for Neuron-Specific Odor Receptor Expression

Anandasankar Ray, Wynand van der Goes van Naters, John R Carlson

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Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer

Kerstin B Meyer, Ana-Teresa Maia, Martin O'Reilly, Andrew E Teschendorff, Suet-Feung Chin, Carlos Caldas, Bruce A. J Ponder

Distinct DNA Exit and Packaging Portals in the Virus Acanthamoeba polyphaga mimivirus

Nathan Zauberman, Yael Mutsafi, Daniel Ben Halevy, Eyal Shimoni, Eugenia Klein, Chuan Xiao, Siyang Sun, Abraham Minsky

Raf Activation Is Regulated by Tyrosine 510 Phosphorylation in Drosophila

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Book Review%2FScience in the Media

The Allure of the Few

Barry W Brook