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March 2006

A human mammary epithelial cell stained to visualize the microtubule spindles (α-tubulin), centrioles (centrin 2), and chromosomes (DAPI). The image is represented by four different color combinations, modified using Photoshop software. Splitting of centriole pairs in primary cells leads to multipolar spindles and causes mis-segregation of chromosomes during mitosis (aneuploidy). See McDermott et al.

Image Credit: Image by Kimberly M. McDermott

Editorial

Being Positive about Selection

Catriona MacCallum, Emma Hill

Community Page

Plant Virus Biodiversity and Ecology

Jonathan D Wren, Marilyn J Roossinck, Richard S Nelson, Kay Scheets, Michael W Palmer, Ulrich Melcher

Research Articles

Reconstructing an Ancestral Mammalian Immune Supercomplex from a Marsupial Major Histocompatibility Complex

Katherine Belov, Janine E Deakin, Anthony T Papenfuss, Michelle L Baker, Sandra D Melman, Hannah V Siddle, Nicolas Gouin, David L Goode, Tobias J Sargeant, Mark D Robinson, Matthew J Wakefield, Shaun Mahony, Joseph G. R Cross, Panayiotis V Benos, Paul B Samollow, Terence P Speed, Jennifer A. Marshall Graves, Robert D Miller

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p16INK4a Prevents Centrosome Dysfunction and Genomic Instability in Primary Cells

Kimberly M McDermott, Jianmin Zhang, Charles R Holst, B. Krystyna Kozakiewicz, Veena Singla, Thea D Tlsty

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Gene Losses during Human Origins

Xiaoxia Wang, Wendy E Grus, Jianzhi Zhang

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Insect Detection of Small Targets Moving in Visual Clutter

Karin Nordström, Paul D Barnett, David C O'Carroll

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Visual Clutter Causes High-Magnitude Errors

Stefano Baldassi, Nicola Megna, David C Burr

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Removing the Threat of Diclofenac to Critically Endangered Asian Vultures

Gerry Swan, Vinasan Naidoo, Richard Cuthbert, Rhys E Green, Deborah J Pain, Devendra Swarup, Vibhu Prakash, Mark Taggart, Lizette Bekker, Devojit Das, Jörg Diekmann, Maria Diekmann, Elmarié Killian, Andy Meharg, Ramesh Chandra Patra, Mohini Saini, Kerri Wolter

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Complete Mitochondrial Genome and Phylogeny of Pleistocene MammothMammuthus primigenius

Evgeny I Rogaev, Yuri K Moliaka, Boris A Malyarchuk, Fyodor A Kondrashov, Miroslava V Derenko, Ilya Chumakov, Anastasia P Grigorenko

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A Stress Surveillance System Based on Calcium and Nitric Oxide in Marine Diatoms

Assaf Vardi, Fabio Formiggini, Raffaella Casotti, Alessandra De Martino, François Ribalet, Antonio Miralto, Chris Bowler

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Glutamine-Expanded Ataxin-7 Alters TFTC/STAGA Recruitment and Chromatin Structure Leading to Photoreceptor Dysfunction

Dominique Helmlinger, Sara Hardy, Gretta Abou-Sleymane, Adrien Eberlin, Aaron B Bowman, Anne Gansmüller, Serge Picaud, Huda Y Zoghbi, Yvon Trottier, Làszlò Tora, Didier Devys

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The Cutaneous Rabbit Illusion Affects Human Primary Sensory Cortex Somatotopically

Felix Blankenburg, Christian C Ruff, Ralf Deichmann, Geraint Rees, Jon Driver

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Correspondence and Other Communications

Neuromedin U and Its Putative Drosophila Homolog hugin

Christoph Melcher, Rüdiger Bader, Steffen Walther, Oleg Simakov, Michael J Pankratz

Book Review%2FScience in the Media

Toward a Climate of Scientific Integrity

Beth A Fischer, Michael J Zigmond