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June 2005

Malaria is transmitted to people and animals by mosquitoes. Malarial sporozoites develop inside oocysts and are released in large numbers into the hemocoel of Anopheles stephensi mosquitoes. This false-colored electron micrograph shows a sporozoite migrating through the cytoplasm of midgut epithelia. See Frevert et al.

Image Credit: Image by Ute Frevert; false color by Margaret Shear

Essay

The Evolution of Norms

Paul R Ehrlich, Simon A Levin

Feature

Community Page

Guidelines for Negotiating Scientific Collaboration

Neil R Smalheiser, Guy A Perkins, Steve Jones

Research Articles

A Scan for Positively Selected Genes in the Genomes of Humans and Chimpanzees

Rasmus Nielsen, Carlos Bustamante, Andrew G Clark, Stephen Glanowski, Timothy B Sackton, Melissa J Hubisz, Adi Fledel-Alon, David M Tanenbaum, Daniel Civello, Thomas J White, John J. Sninsky, Mark D Adams, Michele Cargill

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Ewan P Plant, Gabriela C Pérez-Alvarado, Jonathan L Jacobs, Bani Mukhopadhyay, Mirko Hennig, Jonathan D Dinman

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Inhibition of Mutation and Combating the Evolution of Antibiotic Resistance

Ryan T Cirz, Jodie K Chin, David R Andes, Valérie de Crécy-Lagard, William A Craig, Floyd E Romesberg

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Intravital Observation of Plasmodium berghei Sporozoite Infection of the Liver

Ute Frevert, Sabine Engelmann, Sergine Zougbédé, Jörg Stange, Bruce Ng, Kai Matuschewski, Leonard Liebes, Herman Yee

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Engineering a Dimeric Caspase-9: A Re-evaluation of the Induced Proximity Model for Caspase Activation

Yang Chao, Eric N Shiozaki, Srinivasa M Srinivasula, Daniel J Rigotti, Robert Fairman, Yigong Shi

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Oxygenation Inhibits the Physiological Tissue-Protecting Mechanism and Thereby Exacerbates Acute Inflammatory Lung Injury

Manfred Thiel, Alexander Chouker, Akio Ohta, Edward Jackson, Charles Caldwell, Patrick Smith, Dmitry Lukashev, Iris Bittmann, Michail V Sitkovsky

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Determination of Stromal Signatures in Breast Carcinoma

Robert B West, Dimitry S. A Nuyten, Subbaya Subramanian, Torsten O Nielsen, Christopher L Corless, Brian P Rubin, Kelli Montgomery, Shirley Zhu, Rajiv Patel, Tina Hernandez-Boussard, John R Goldblum, Patrick O Brown, Marc van de Vijver, Matt van de Rijn

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Neuronal Migration and Ventral Subtype Identity in the Telencephalon Depend on SOX1

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Function of a Fly Motion-Sensitive Neuron Matches Eye Movements during Free Flight

Roland Kern, J. H van Hateren, Christian Michaelis, Jens Peter Lindemann, Martin Egelhaaf

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