{"text_format":"1","workbook":"xlsx","n_sheets":12,"sheets":["Fig 4Ci","Fig 4Cii","Fig 5A","Fig 5B","Fig 5C","Fig 5D","Fig 5E","Fig 6A","Fig 6B","Fig 8D","Fig 8E","Table1"],"not_rendered":{"charts":0,"images":0,"macros":0,"external_links":0,"defined_names":0,"comments":0,"pivot_tables":0},"unopened":[],"bounds":{"document_bytes":16777216,"sheet_cells":100000,"rows_first":2000,"rows_last":500,"rows_between":2000,"halvings":0,"cell_chars":16384,"cell_head_chars":4096},"cells_cut":0,"cells_raw":0,"read":"whole","date_system":"1900"}

{"sheet":"Fig 4Ci","index":0,"n_rows":71,"n_cols":15,"rows_kept":71,"cut":false,"hidden":false,"merged":[[0,1,0,7],[0,8,0,14]]}
["Minutes before (-) or after (+) shuttle","Neutrophils",null,null,null,null,null,null,"Macrophage"]
[-20,5.3,17,4,10.199999999999999,27,26.2,39.6,21.7,19,33.9,15.6,14.7,52,20.2]
[-15,4.2,9.3000000000000007,5.0999999999999996,28.2,26.4,17.600000000000001,42,16.3,12.2,20.2,12.2,12,39.5,22.9]
[-10,4,3,7.8,32,14,5.5,41.7,8,10,9.1,18,8.6999999999999993,36.200000000000003,13.9]
[-5,3,4,3.6,4,17,5.6,26.1,3,10,5,15,9,18.3,15.7]
[0,6,4,2,4,6,5,8,4,5,3,7,8,6,15]
["+5",30,8,28,17,32,26.1,35.6,8,3,21,3,5,10.199999999999999,15.6]
["+10",77,10,44,28,65,5.7,7.23,9,7,20,5,11,25.7,16.899999999999999]
["+15",81.599999999999994,14.3,49.5,28.6,57.2,7.1,15,18.899999999999999,14,19.2,5.6,19,10.3,10.5]
["+20",53.6,25,66.5,29.2,43.5,9.9,28.6,27,20,24.7,12.2,22.9,32.9,10.9]
[]
[]
[]
[" \"neutrophils at t=0\" vs. \"neutrophils-20 mins\""]
["Paired t test"]
["P value",1.7500000000000002E-2]
["P value summary","*"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=3.092, df=7"]
["Number of pairs",8]
[]
[]
["\"neutrophils+20 mins\" vs. \"neutrophils at t=0\""]
["Paired t test"]
["P value",8.9999999999999998E-4]
["P value summary","***"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=4.844, df=9"]
["Number of pairs",10]
[]
[]
["\"neutrophils+5 mins\" vs. \"neutrophils-5mins\""]
["Paired t test"]
["P value",3.44E-2]
["P value summary","*"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","One-tailed"]
["t, df","t=2.065, df=9"]
["Number of pairs",10]
[]
[]
["\"macrophages at t=0\" vs. \"macrophages-20 mins\""]
["Paired t test"]
["P value",1.4999999999999999E-2]
["P value summary","*"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=3.203, df=7"]
["Number of pairs",8]
[]
[]
["\"macrophages+20 mins\" vs. \"macrophages at t=0\""]
["Paired t test"]
["P value",2.3999999999999998E-3]
["P value summary","**"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=4.181, df=9"]
["Number of pairs",10]
[]
[]
[]
["\"macrophages+20 mins\" vs. \"neutrophils+20 mins\""]
["Unpaired t test"]
["P value",2.5100000000000001E-2]
["P value summary","*"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","One-tailed"]
["t, df","t=2.117, df=16"]

{"sheet":"Fig 4Cii","index":1,"n_rows":71,"n_cols":15,"rows_kept":71,"cut":false,"hidden":false,"merged":[[0,1,0,7],[0,8,0,14]]}
["Minutes before (-) or after (+) shuttle","Neutrophils",null,null,null,null,null,null,"Macrophage"]
[-20,5.3,17,4,10.199999999999999,27,26.2,39.6,21.7,19,33.9,15.6,14.7,52,20.2]
[-15,4.2,9.3000000000000007,5.0999999999999996,28.2,26.4,17.600000000000001,42,16.3,12.2,20.2,12.2,12,39.5,22.9]
[-10,4,3,7.8,32,14,5.5,41.7,8,10,9.1,18,8.6999999999999993,36.200000000000003,13.9]
[-5,3,4,3.6,4,17,5.6,26.1,3,10,5,15,9,18.3,15.7]
[0,6,4,2,4,6,5,8,4,5,3,7,8,6,15]
["+5",30,8,28,17,32,26.1,35.6,8,3,21,3,5,10.199999999999999,15.6]
["+10",77,10,44,28,65,5.7,7.23,9,7,20,5,11,25.7,16.899999999999999]
["+15",81.599999999999994,14.3,49.5,28.6,57.2,7.1,15,18.899999999999999,14,19.2,5.6,19,10.3,10.5]
["+20",53.6,25,66.5,29.2,43.5,9.9,28.6,27,20,24.7,12.2,22.9,32.9,10.9]
[]
[]
[]
[" \"neutrophils at t=0\" vs. \"neutrophils-20 mins\""]
["Paired t test"]
["P value",8.3299999999999999E-2]
["P value summary","ns"]
["Significantly different (P < 0.05)?","No"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=2.075, df=6"]
["Number of pairs",7]
[]
[]
["\"neutrophils+20 mins\" vs. \"neutrophils at t=0\""]
["Paired t test"]
["P value",5.5999999999999999E-3]
["P value summary","**"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=4.217, df=6"]
["Number of pairs",7]
[]
[]
["\"neutrophils+5 mins\" vs. \"neutrophils-5mins\""]
["Paired t test"]
["P value",1E-3]
["P value summary","**"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","One-tailed"]
["t, df","t=5.199, df=6"]
["Number of pairs",7]
[]
[]
["\"macrophages at t=0\" vs. \"macrophages-20 mins\""]
["Paired t test"]
["P value",1.7299999999999999E-2]
["P value summary","*"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=3.259, df=6"]
["Number of pairs",7]
[]
[]
["\"macrophages+20 mins\" vs. \"macrophages at t=0\""]
["Paired t test"]
["P value",1.1900000000000001E-2]
["P value summary","*"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","Two-tailed"]
["t, df","t=3.564, df=6"]
["Number of pairs",7]
[]
[]
[]
["\"macrophages+20 mins\" vs. \"neutrophils+20 mins\""]
["Unpaired t test"]
["P value",3.8800000000000001E-2]
["P value summary","*"]
["Significantly different (P < 0.05)?","Yes"]
["One- or two-tailed P value?","One-tailed"]
["t, df","t=1.930, df=12"]

{"sheet":"Fig 5A","index":2,"n_rows":22,"n_cols":5,"rows_kept":22,"cut":false,"hidden":false,"merged":[[0,0,1,0]]}
["Shuttle #","Period of donor neutrophil spore carriage","Shuttle time (in the movie) ","Period of contact between shuttling cells","Period of conidial transfer"]
[null,"(min)","(min)","(min)","(min)"]
[7,8,8,6.5,1.8]
["2019-01-08",26,36,4,0.8]
["2019-02-08",72,72,104,0.9]
[18,14,14,4.5999999999999996,3]
[25,27,35,10,1]
[27,15,21,4,1.8]
[31,60,97,53.3,1.1000000000000001]
[43,25,30,5.6,1]
[46,95,97,8.5,4]
[48,14,14,5,1.8]
[57,15,65,9.6,2.2999999999999998]
["59-3",20,61,5.0999999999999996,1.6]
["59-4",4,14,1.3,0.6]
["60-1",62,121,25.6,1.6]
["61-3",78,126,31.3,1.3]
["63-1",30,30,11.5,1.1000000000000001]
["63-4-1",28,160,10.6,1.2]
["63-4-2",183,198,3,1.2]
["66-48",17,108,7,0.6]
["66-50",6,178,5.6,2.5]

{"sheet":"Fig 5B","index":3,"n_rows":59,"n_cols":2,"rows_kept":59,"cut":false,"hidden":false,"merged":[[0,0,0,1]]}
["Number of spores at T=0 min"]
["Shuttle: NO","Shuttle: YES"]
[22,10]
[30,50]
[15,14]
[10,15]
[16,5]
[13,20]
[8,16]
[15,20]
[10,40]
[23,3]
[20,70]
[20,60]
[35,40]
[57]
[13]
[12]
[50]
[45]
[5]
[10]
[35]
[22]
[8]
[17]
[27]
[18]
[40]
[7]
[17]
[10]
[40]
[50]
[23]
[50]
[35]
[20]
[10]
[40]
[20]
[8]
[4]
[15]
[14]
[21]
[15]
[7]
[5]
[8]
[22]
[50]
[50]
[26]
[60]
[60]
[45]
[80]
[30]

{"sheet":"Fig 5C","index":4,"n_rows":18,"n_cols":2,"rows_kept":18,"cut":false,"hidden":false,"merged":[[0,0,0,1]]}
["Number of spores at T=0 min"]
["Shuttle: NO","Shuttle: YES"]
[70,50]
[45,40]
[13,10]
[27,17]
[14,25]
[33,100]
[9]
[35]
[40]
[23]
[18]
[34]
[40]
[70]
[33]
[17]

{"sheet":"Fig 5D","index":5,"n_rows":35,"n_cols":5,"rows_kept":35,"cut":false,"hidden":false,"merged":[]}
["shuttling \ncontacts","non-shuttling \ncontacts"]
[1.7,0.5,null,"\"non-shuttling contacts\" vs. \" shuttling contacts\""]
[3,1,null,"Mann Whitney test"]
[4,1,null,"P value","<0.0001"]
[4.0999999999999996,1,null,"Exact or approximate P value?","Exact"]
[4.7,1,null,"P value summary","****"]
[4.9000000000000004,1,null,"Significantly different (P < 0.05)?","Yes"]
[5.0999999999999996,1,null,"One- or two-tailed P value?","Two-tailed"]
[5.6,1,null,"Sum of ranks in column A,B","775 , 710"]
[5.7,1,null,"Mann-Whitney U",115]
[6.5,1]
[6.9,2]
[8.5,2]
[9.6999999999999993,2]
[10.1,2]
[10.7,2]
[11.5,2]
[25.7,2]
[31.2,2]
[53.3,3]
[104,3]
[null,3]
[null,3]
[null,3]
[null,4]
[null,5]
[null,5]
[null,5]
[null,7]
[null,7]
[null,7]
[null,7]
[null,7]
[null,8]
[null,10]

{"sheet":"Fig 5E","index":6,"n_rows":28,"n_cols":4,"rows_kept":28,"cut":false,"hidden":false,"merged":[]}
["T. marneffei","A. fumigatus"]
[10,121]
[36,126]
[72,30]
[14,200]
[33,178]
[21,108]
[94]
[30]
[97]
[14]
[65]
[61]
[14]
[]
[]
[]
["P value and statistical significance"]
["Test","Fisher's exact test"]
["P value",1.66E-2]
["P value summary","*"]
["One- or two-sided","Two-sided"]
["Statistically significant (P < 0.05)?","Yes"]
[]
["Data analyzed","<60min",">60min","Total"]
["Tm",10,3,13]
["Af",1,6,7]
["Total",11,9,20]

{"sheet":"Fig 6A","index":7,"n_rows":8,"n_cols":6,"rows_kept":8,"cut":false,"hidden":false,"merged":[[0,1,0,2],[0,4,0,5]]}
[null,"Absolute values",null,null,"Percentage as plotted"]
[null,"shuttle: Yes","shuttle: No",null,"shuttle: Yes","shuttle: No"]
["Live TM",13,56,null,19,81]
["Live AF",6,16,null,27,73]
["Mut AF",4,23,null,15,85]
["Dead TM",2,1,null,67,33]
["Dead AF",2,11,null,15,85]
["Zymosan",3,3,null,50,50]

{"sheet":"Fig 6B","index":8,"n_rows":33,"n_cols":6,"rows_kept":33,"cut":false,"hidden":false,"merged":[[0,1,0,2],[0,4,0,5]]}
[null,"Absolute values",null,null,"Percentage as plotted"]
[null,"shuttle: Yes","shuttle: No",null,"shuttle: Yes","shuttle: No"]
["Beads",0,18,null,0,100]
["Beads\n+glucan",10,12,null,41,59]
["Coated beads+enz",3,21,null,12,88]
[]
[]
[]
["P value and statistical significance"]
["Test","Fisher's exact test"]
["P value",8.0000000000000004E-4]
["P value summary","***"]
["One- or two-sided","Two-sided"]
["Statistically significant (P < 0.05)?","Yes"]
[]
["Data analyzed","movies with huttle","movies without shuttle","Total"]
["beads",0,18,18]
["beads\n+glucan",10,12,22]
["Total",10,30,40]
[]
[]
[]
["P value and statistical significance"]
["Test","Fisher's exact test"]
["P value",2.12E-2]
["P value summary","*"]
["One- or two-sided","Two-sided"]
["Statistically significant (P < 0.05)?","Yes"]
[]
["Data analyzed","movies with huttle","movies without shuttle","Total"]
["beads\n+glucan",10,12,22]
["caoted beads+enz",3,21,24]
["Total",13,33,46]

{"sheet":"Fig 8D","index":9,"n_rows":99,"n_cols":2,"rows_kept":99,"cut":false,"hidden":false,"merged":[]}
["Exp 1","Exp 2"]
[2,1]
[3,1]
[4,1]
[5,2]
[5,3]
[5,5]
[6,5]
[6,5]
[7,5]
[8,5]
[8,5]
[8,5]
[9,5]
[10,5]
[10,5]
[10,6]
[10,6]
[12,7]
[12,7]
[13,8]
[15,8]
[15,10]
[17,10]
[20,10]
[20,10]
[22,10]
[24,12]
[25,12]
[31,13]
[35,13]
[36,13]
[37,13]
[39,14]
[40,14]
[40,15]
[40,15]
[40,15]
[40,15]
[41,18]
[43,20]
[45,20]
[47,20]
[47,20]
[50,20]
[51,20]
[51,20]
[52,20]
[52,21]
[53,22]
[55,22]
[55,23]
[55,23]
[56,24]
[59,24]
[61,24]
[66,25]
[73,26]
[74,27]
[76,27]
[76,27]
[78,29]
[79,29]
[79,30]
[80,30]
[89,30]
[90,30]
[null,31]
[null,31]
[null,32]
[null,33]
[null,33]
[null,33]
[null,34]
[null,34]
[null,36]
[null,36]
[null,36]
[null,37]
[null,37]
[null,40]
[null,41]
[null,41]
[null,46]
[null,46]
[null,47]
[null,47]
[null,47]
[null,49]
[null,52]
[null,53]
[null,53]
[null,54]
[null,56]
[null,60]
[null,61]
[null,62]
[null,70]
[null,83]

{"sheet":"Fig 8E","index":10,"n_rows":166,"n_cols":6,"rows_kept":166,"cut":false,"hidden":false,"merged":[[0,1,0,2]]}
[null,"Paired data for shuttled spores"]
["Background","in Neutrophil","in Macrophage"]
[1715,4915,6279]
[1664,3720,4516,null,"\"in Neutrophil\" vs. \"Background\""]
[1742,6272,7340,null,"Unpaired t test"]
[1641,3109,4429,null,"P value","<0.0001"]
[1797,3476,6942,null,"P value summary","****"]
[1891,4129,5913,null,"Significantly different (P < 0.05)?","Yes"]
[1944,3620,6222,null,"One- or two-tailed P value?","Two-tailed"]
[1906,5958,5543,null,"t, df","t=15.34, df=262"]
[1898,7779,9882]
[1844,6546,8850]
[1778,3995,4640,null,"\"in Macrophage\" vs. \"in Neutrophil\""]
[1639,7807,11244,null,"Paired t test"]
[1584,3416,4661,null,"P value","<0.0001"]
[1651,3635,4662,null,"P value summary","****"]
[1606,2740,4788,null,"Significantly different (P < 0.05)?","Yes"]
[1747,5049,5490,null,"One- or two-tailed P value?","Two-tailed"]
[1697,6706,8925,null,"t, df","t=11.21, df=163"]
[1653,7593,8892,null,"Number of pairs",164]
[1631,7060,7225]
[1626,5794,8482]
[1643,5523,7600]
[1659,5788,8254]
[1656,4243,6722]
[1586,3402,5711]
[1540,2550,5310]
[1634,3320,5243]
[1750,6720,8910]
[1656,5373,7112]
[1789,3239,5974]
[1763,3834,4422]
[1823,3461,5020]
[1800,9942,10896]
[1881,2354,13394]
[1849,7182,7962]
[1728,7739,9821]
[1686,4156,3704]
[1769,11697,6352]
[1885,10732,18546]
[1834,5353,11482]
[1889,3261,5058]
[1832,5914,9538]
[1899,7132,7637]
[1842,4456,5334]
[1917,6912,12657]
[1814,5303,9023]
[1787,3380,5504]
[1759,4959,7350]
[1741,7359,10556]
[1764,5519,4099]
[1751,4743,4390]
[1488,4811,6036]
[1502,4034,4117]
[1447,5989,4567]
[1468,2651,3937]
[1538,2818,6895]
[1460,5639,6177]
[1468,5476,6162]
[1533,3600,4168]
[1704,5291,5451]
[1605,8858,9163]
[1610,2930,9533]
[1702,5814,8143]
[1631,3154,4775]
[1599,8080,6516]
[1651,3748,4292]
[1576,8071,14916]
[1630,3150,6821]
[1595,2526,6713]
[1659,5803,11400]
[1714,5507,6437]
[1737,8070,8238]
[1753,2999,9782]
[1634,5512,12090]
[1737,2893,9155]
[1632,11266,7952]
[1615,4424,10810]
[1638,3436,4718]
[1583,3310,8613]
[1643,5165,8732]
[1661,3477,4565]
[1663,4126,6522]
[1655,3111,3663]
[1710,3273,9664]
[1736,4195,9936]
[1709,7013,8195]
[1737,5616,4424]
[1846,4466,7944]
[1791,3862,8090]
[1773,3263,7382]
[1831,3208,6749]
[1743,6512,5519]
[1666,8729,9579]
[1576,3939,11689]
[1584,3553,7496]
[1536,5793,13651]
[1539,8956,14053]
[1575,3171,4222]
[1565,4375,10134]
[1575,3014,5269]
[2129,4234,6999]
[null,5890,9693]
[null,6780,10606]
[null,3206,1933]
[null,4789,6273]
[null,3146,11011]
[null,6591,7453]
[null,11121,15829]
[null,4702,11217]
[null,4726,3503]
[null,5975,4480]
[null,10594,8879]
[null,3795,11579]
[null,11897,9605]
[null,6287,8383]
[null,3231,6668]
[null,4305,10544]
[null,7827,16958]
[null,6331,17315]
[null,5203,16488]
[null,3061,5414]
[null,4635,8844]
[null,4131,7610]
[null,4862,8934]
[null,3182,2144]
[null,11253,4750]
[null,3065,11558]
[null,4465,6485]
[null,3805,4658]
[null,6327,5823]
[null,10510,17908]
[null,7731,8088]
[null,13628,19143]
[null,3923,11014]
[null,3992,9193]
[null,3385,19342]
[null,4193,12771]
[null,6756,7116]
[null,10640,11394]
[null,3476,6790]
[null,3421,5176]
[null,5301,13631]
[null,3477,12035]
[null,3639,11490]
[null,4195,5394]
[null,3275,14807]
[null,4536,7035]
[null,2569,2369]
[null,3840,4971]
[null,7222,19177]
[null,3507,6068]
[null,2905,7059]
[null,6711,16081]
[null,2731,12975]
[null,2981,15781]
[null,5038,7345]
[null,3134,3136]
[null,5847,9328]
[null,2509,3658]
[null,6507,5305]
[null,3842,7608]
[null,3343,5363]
[null,4027,9858]
[null,6241,7777]
[null,3133,6256]

{"sheet":"Table1","index":11,"n_rows":31,"n_cols":14,"rows_kept":31,"cut":false,"hidden":false,"merged":[[22,0,31,0],[22,1,24,1],[22,2,24,2],[22,7,24,7],[22,8,24,8],[25,1,31,1],[25,2,31,2],[25,7,31,7],[25,8,31,8],[5,3,5,4],[5,5,5,6],[7,0,12,0],[7,9,8,9],[10,9,11,9],[0,0,6,0],[0,1,3,2],[0,3,0,6],[0,7,3,7],[1,3,1,6],[2,3,2,6],[3,3,3,6],[4,3,4,4],[4,5,4,6],[4,7,6,7],[13,0,21,0],[13,1,16,1],[13,2,16,2],[13,7,16,7],[13,8,16,8],[17,1,20,1],[17,2,20,2],[17,7,20,7],[17,8,20,8]]}
["Experiment*","Shuttling cell ",null,"Cell number at start ",null,null,null,null,"Shuttles","p-value ¶"]
[null,null,null,"5th movie frame"]
[null,null,null,null,null,null,null,null,null,"Wildtype "]
[null,null,null,null,null,null,null,null,"mean±sd","vs"]
[null,"Donor neutrophils","Recipient macrophages","Neutrophils",null,"Macrophages",null,"Number of wells scored",null,"Dectin-1-/-"]
[null,"Genotype - source","Genotype","number / scored area",null,"number / scored area"]
[null,null,null,"Loaded","Total","Loaded","Total"]
[1,"Wildtype – BM","Wildtype",22,204,31,81,1,2,"n/a"]
[null,"Wildtype – BM","Dectin-1-/-",38,405,36,61,1,1]
[]
[null,"Wildtype – PB","Wildtype",18,203,41,114,1,1,"n/a"]
[null,"Wildtype – PB","Dectin-1-/-",15,248,34,90,1,0]
[]
[2,"Wildtype – BM","Wildtype",333,809,54,84,3,"17.3±4.7",null,null,null,"\"exp-2 ko\" vs. \"exp-2 wt\""]
[null,null,null,219,577,49,57,null,null,1.15E-2,null,null,"Unpaired t test"]
[null,null,null,517,1080,77,88,null,null,null,null,null,"P value",1.15E-2]
[null,null,null,null,null,null,null,null,null,null,null,null,"P value summary","*"]
[null,"Wildtype – BM","Dectin-1-/-",366,756,43,73,3,"4.7±1.5",null,null,null,"Significantly different (P < 0.05)?","Yes"]
[null,null,null,464,1025,37,45,null,null,null,null,null,"One- or two-tailed P value?","Two-tailed"]
[null,null,null,424,871,62,75,null,null,null,null,null,"t, df","t=4.417, df=4"]
[]
[]
[3,"Wildtype – BM","Wildtype",373,836,26,36,2,"18.5±3.5",null,null,null,"\"exp-3 ko\" vs. \"exp-3 wt\""]
[null,null,null,492,946,47,72,null,null,1E-4,null,null,"Unpaired t test"]
[null,null,null,null,null,null,null,null,null,null,null,null,"P value",1E-4]
[null,"Wildtype – BM","Dectin-1-/-",297,650,57,77,6,"5.0±1.2 ",null,null,null,"P value summary","***"]
[null,null,null,281,612,38,53,null,null,null,null,null,"Significantly different (P < 0.05)?","Yes"]
[null,null,null,390,972,41,60,null,null,null,null,null,"One- or two-tailed P value?","Two-tailed"]
[null,null,null,231,516,47,70,null,null,null,null,null,"t, df","t=8.945, df=6"]
[null,null,null,334,682,68,120]
[null,null,null,385,715,76,104]