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Integrative illustration for coronavirus outreach

Fig 2

Coronavirus replication and budding.

This illustration shows a cross-section through a cell infected with a coronavirus such as SARS-CoV-2. It shows a time point when the virus is actively replicating, and new viruses are being created. The cell’s molecules are shown in blues and greens, and the viral molecules are shown in reds and purples. The illustration integrates the current state of knowledge, but many aspects of the virus and its life cycle are still actively being studied, so portions of the illustration are speculative. Note that some features, such as RNA, needed to be slightly exaggerated in size/width, given the minimal size of features that could be depicted using black outlines of discernable width at the consistent magnification of 1,000,000× that was used for the original watercolor painting. SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.

Fig 2