Knowledge-guided analysis of "omics" data using the KnowEnG cloud platform
Fig 1
(A) Typical workflow steps for KnowEnG: genomic analysis on the cloud. (B) Analytical functionalities are organized as “pipelines” for common tasks such as clustering, gene prioritization, gene set analysis, and signature analysis. Each pipeline offers various options to customize the analysis, including use of prior knowledge. (C) The KnowEnG Knowledge Network represents prior knowledge that may be used during analysis. Nodes in the network represent genes and biological properties, and edges represent either annotations of gene properties or gene-gene relationships. Network contents are summarized on the left with logos of data sources shown on the right. KnowEnG, Knowledge Engine for Genomics; TCGA, the Cancer Genome Atlas.