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Tissue tropism and transmission ecology predict virulence of human RNA viruses

Table 1

Predictive performance metrics for classification tree and random forest model.

Sensitivity, specificity, NPV (proportion of ‘nonsevere’ predictions that correctly matched literature rating), TSS (sensitivity + specificity − 1), and AUROC for predictive model methods applied to predict virulence of viruses within the test set. Random forest diagnostics indicate mean values across 200 training/test partitions. Supporting data are available via figshare: 10.6084/m9.figshare.7406441.v3 (

Table 1