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Selective Inflammatory Pain Insensitivity in the African Naked Mole-Rat (Heterocephalus glaber)

Figure 2

Recordings from Naked Mole-Rat Single Afferent Fibers in the Saphenous Skin Nerve Preparation

(A) Example of a recording made from a single C-fiber afferent and its response to mechanical stimulation, indentation of 192 μm.

(B) Stimulus-response relations of mechanosensitive Aδ and C-fiber afferents for a standard series of ascending displacement stimuli applied to the receptive fields.

(C) Example of a polymodal C-fiber (CMH) response to application of heated bath solution onto its receptive field.

(D) Averaged spike rates for 17 CMH fibers before and during the heating stimulus. An additional 13 CM fibers did not respond to heating.

Figure 2