Topological Reorganization of Odor Representations in the Olfactory Bulb
(A) Top and middle: Three-dimensional MC activity patterns evoked by two related stimuli (Trp and Tyr) in successive 256-ms time bins (same as in Figure 5A; same conventions; n = 131 MCs). Bottom: overlay. The size of spheres represents the magnitude of the larger response to the two stimuli; the color indicates the response ratio. Pure colors (yellow or cyan) indicate that a given MC responded predominantly to one of the two stimuli; black indicates similar responses to both stimuli. Arrow indicates high degree of overlap in focus during the initial phase of the response. Distance between ticks is 50 μm on all axes. Orientation is as indicated: anterior to posterior (A–P), medial to lateral (M–L), and dorsal to ventral (D–V).
(B) Further examples of MC response patterns evoked by chemically related stimuli (overlays; same conventions as in [A]).
(C) Overlay of MC response patterns evoked by two dissimilar stimuli. Same conventions as in (A).