Phase variation of a signal transduction system controls Clostridioides difficile colony morphology, motility, and virulence

• Elizabeth M. Garrett,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Ognjen Sekulovic,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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• Daniela Wetzel,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Emory University, Rollins Research Center, Atlanta, Georgia, United States of America

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• Joshua B. Jones,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Emory University, Rollins Research Center, Atlanta, Georgia, United States of America

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• Adrianne N. Edwards,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Emory University, Rollins Research Center, Atlanta, Georgia, United States of America

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• Germán Vargas-Cuebas,

  Roles Investigation

  Affiliation Department of Microbiology and Immunology, Emory University, Rollins Research Center, Atlanta, Georgia, United States of America

  http://orcid.org/0000-0002-8906-032X

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• Shonna M. McBride,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Department of Microbiology and Immunology, Emory University, Rollins Research Center, Atlanta, Georgia, United States of America

  http://orcid.org/0000-0001-6221-714X

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• Rita Tamayo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: Rita_tamayo@med.unc.edu

  Affiliation Department of Microbiology and Immunology, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0002-3745-3316

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