Inhibitor of the Tyrosine Phosphatase STEP Reverses Cognitive Deficits in a Mouse Model of Alzheimer's Disease

• Jian Xu,

  Affiliation Child Study Center, Yale University, New Haven, Connecticut, United States of America

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• Manavi Chatterjee,

  Affiliation Child Study Center, Yale University, New Haven, Connecticut, United States of America

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• Tyler D. Baguley,

  Affiliation Department of Chemistry, Yale University, New Haven, Connecticut, United States of America

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• Jonathan Brouillette,

  Affiliation Child Study Center, Yale University, New Haven, Connecticut, United States of America

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• Pradeep Kurup,

  Affiliation Child Study Center, Yale University, New Haven, Connecticut, United States of America

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• Debolina Ghosh,

  Affiliation Child Study Center, Yale University, New Haven, Connecticut, United States of America

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• Jean Kanyo,

  Affiliation Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

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• Yang Zhang,

  Affiliations Child Study Center, Yale University, New Haven, Connecticut, United States of America, Laboratory for Drug Discovery in Neurodegeneration and Department of Neurology, Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America

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• Kathleen Seyb,

  Affiliation Laboratory for Drug Discovery in Neurodegeneration and Department of Neurology, Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America

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• Chimezie Ononenyi,

  Affiliation Child Study Center, Yale University, New Haven, Connecticut, United States of America

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• Ethan Foscue,

  Affiliation Child Study Center, Yale University, New Haven, Connecticut, United States of America

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• George M. Anderson,

  Affiliations Child Study Center, Yale University, New Haven, Connecticut, United States of America, Department of Laboratory Medicine, Yale University, New Haven, Connecticut, United States of America

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• Jodi Gresack,

  Affiliation Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, United States of America

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• Gregory D. Cuny,

  Affiliation Laboratory for Drug Discovery in Neurodegeneration and Department of Neurology, Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America

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• Marcie A. Glicksman,

  Affiliation Laboratory for Drug Discovery in Neurodegeneration and Department of Neurology, Brigham and Women's Hospital, Cambridge, Massachusetts, United States of America

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• Paul Greengard,

  Affiliation Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, United States of America

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• TuKiet T. Lam,

  Affiliation Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut, United States of America

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• Lutz Tautz,

  Affiliation Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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• Angus C. Nairn,

  Affiliation Department of Psychiatry, Yale University, New Haven, Connecticut, United States of America

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• Jonathan A. Ellman,

  Affiliation Department of Chemistry, Yale University, New Haven, Connecticut, United States of America

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•  [ ... ],
• Paul J. Lombroso

  * E-mail: paul.lombroso@yale.edu

  Affiliations Child Study Center, Yale University, New Haven, Connecticut, United States of America, Department of Psychiatry, Yale University, New Haven, Connecticut, United States of America, Department of Neurobiology, Yale University, New Haven, Connecticut, United States of America

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