The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

Tokameh Mahmoudi; Sylvia F. Boj; Pantelis Hatzis; Vivian S. W. Li; Nadia Taouatas; Robert G. J. Vries; Hans Teunissen; Harry Begthel; Jeroen Korving; Shabaz Mohammed; Albert J. R. Heck; Hans Clevers

doi:10.1371/journal.pbio.1000539

Loading metrics

Open Access

Peer-reviewed

Research Article

The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

Tokameh Mahmoudi ,

* E-mail: t.mahmoudi@erasmusmc.nl

Current address: Erasmus University Medical Center, Department of Biochemistry, Rotterdam, The Netherlands

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Sylvia F. Boj ,

Contributed equally to this work with: Sylvia F. Boj, Pantelis Hatzis

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Pantelis Hatzis ,

Contributed equally to this work with: Sylvia F. Boj, Pantelis Hatzis

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Vivian S. W. Li,

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Nadia Taouatas,

Affiliation Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University, Utrecht, The Netherlands
⨯
Robert G. J. Vries,

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Hans Teunissen,

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Harry Begthel,

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Jeroen Korving,

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯
Shabaz Mohammed,

Affiliation Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University, Utrecht, The Netherlands
⨯
Albert J. R. Heck,

Affiliation Biomolecular Mass Spectrometry and Proteomics Group, Utrecht University, Utrecht, The Netherlands
⨯
Hans Clevers

Affiliation Hubrecht Institute and University Medical Centre Utrecht, Utrecht, The Netherlands
⨯

The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis

Tokameh Mahmoudi,
Sylvia F. Boj,
Pantelis Hatzis,
Vivian S. W. Li,
Nadia Taouatas,
Robert G. J. Vries,
Hans Teunissen,
Harry Begthel,
Jeroen Korving,
Shabaz Mohammed

Published: November 16, 2010
https://doi.org/10.1371/journal.pbio.1000539

Reader Comments (1)

Post a new comment on this article

0 Responses

19 Nov 2014
10:33 GMT
Most Recent

Dear readers, Posted by Tokameh on 19 Nov 2014 at 10:33 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gastrointestinal tract
Is the Subject Area "Gastrointestinal tract" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
Zebrafish
Is the Subject Area "Zebrafish" applicable to this article?

Thanks for your feedback.
Small interfering RNA
Is the Subject Area "Small interfering RNA" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
DNA transcription
Is the Subject Area "DNA transcription" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Chromatin
Is the Subject Area "Chromatin" applicable to this article?

Thanks for your feedback.