About the Authors

Robert K. Bradley

Current address: Computational Biology Program, Public Health Sciences Division, and Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Jason Merkin

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Nicole J. Lambert

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Christopher B. Burge

cburge@mit.edu

Affiliation Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: RKB JM NJL CBB. Performed the experiments: RKB NL JM. Analyzed the data: RKB. Contributed reagents/materials/analysis tools: JM. Wrote the paper: RKB CBB.