About the Authors
- Claire V. Harper
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Current address: Michael Smith Building, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
Affiliation Centre for Cell Imaging, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
- Bärbel Finkenstädt
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Affiliation Department of Statistics, University of Warwick, Coventry, United Kingdom
- Dan J. Woodcock
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Affiliation Warwick Systems Biology Centre, University of Warwick, United Kingdom
- Sönke Friedrichsen
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Affiliation Endocrinology Group, School of Biomedicine, University of Manchester, Manchester, United Kingdom
- Sabrina Semprini
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Affiliation Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
- Louise Ashall
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Current address: Michael Smith Building, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
Affiliation Centre for Cell Imaging, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
- David G. Spiller
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Current address: Michael Smith Building, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
Affiliation Centre for Cell Imaging, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
- John J. Mullins
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Affiliation Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
- David A. Rand
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* E-mail: d.a.rand@warwick.ac.uk (DAR); julian.davis@manchester.ac.uk (JRED); mike.white@manchester.ac.uk (MRHW)
Affiliation Warwick Systems Biology Centre, University of Warwick, United Kingdom
- Julian R. E. Davis
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* E-mail: d.a.rand@warwick.ac.uk (DAR); julian.davis@manchester.ac.uk (JRED); mike.white@manchester.ac.uk (MRHW)
Affiliation Endocrinology Group, School of Biomedicine, University of Manchester, Manchester, United Kingdom
- Michael R. H. White
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* E-mail: d.a.rand@warwick.ac.uk (DAR); julian.davis@manchester.ac.uk (JRED); mike.white@manchester.ac.uk (MRHW)
Current address: Michael Smith Building, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.
Affiliation Centre for Cell Imaging, School of Biological Sciences, University of Liverpool, Liverpool, United Kingdom
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: MRHW JRED CVH. Performed the experiments: CVH. Analyzed the data: CVH BF DJW. Contributed reagents/materials/analysis tools: SF SS JJM DGS LA. Wrote the paper: MRHW CVH DAR JRED. Managed the Centre for Cell Imaging: DGS. Designed and developed the statistical algorithms: BF DJW. Prepared the supporting information: BF CVH DJW. Planned and led the mathematical analysis: DAR. Initiated and directed the project: MRHW JRED.