Prion Switching in Response to Environmental Stress

Jens Tyedmers; Maria Lucia Madariaga; Susan Lindquist

doi:10.1371/journal.pbio.0060294

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Open Access

Peer-reviewed

Research Article

Prion Switching in Response to Environmental Stress

Jens Tyedmers ,

Contributed equally to this work with: Jens Tyedmers, Maria Lucia Madariaga

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America
⨯
Maria Lucia Madariaga ,

Contributed equally to this work with: Jens Tyedmers, Maria Lucia Madariaga

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America , Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Susan Lindquist

*To whom correspondence should be addressed. E-mail: Lindquist_admin@wi.mit.edu

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America , Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯

Prion Switching in Response to Environmental Stress

Jens Tyedmers,
Maria Lucia Madariaga,
Susan Lindquist

Published: November 25, 2008
https://doi.org/10.1371/journal.pbio.0060294

About the Authors

Jens Tyedmers

Contributed equally to this work with: Jens Tyedmers, Maria Lucia Madariaga

Affiliation Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America

Maria Lucia Madariaga

Contributed equally to this work with: Jens Tyedmers, Maria Lucia Madariaga

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America , Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, Massachusetts, United States of America

Susan Lindquist

*To whom correspondence should be addressed. E-mail: Lindquist_admin@wi.mit.edu

Affiliations Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America , Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SL was involved in study design. JT and MLM designed the study and analyzed data. JT, MLM, and SL wrote the manuscript.

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Toxicity
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Hyperexpression techniques
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Prions
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Cellular stress responses
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Genetic polymorphism
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Genetics
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Yeast
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Fungal evolution
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