About the Authors

Young-In Chi

To whom correspondence should be addressed. E-mail: ychi@uky.edu (Y-IC); wgscott@chemistry.ucsc.edu (WGS); SHKim@cchem.berkeley.edu (SHK)

Affiliation Center for Structural Biology, Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America

Monika Martick

Affiliation Center for the Molecular Biology of RNA, Sinsheimer Laboratory, University of California at Santa Cruz, Santa Cruz, California, United States of America

Monica Lares

Affiliation Center for the Molecular Biology of RNA, Sinsheimer Laboratory, University of California at Santa Cruz, Santa Cruz, California, United States of America

Rosalind Kim

Affiliation Department of Chemistry, University of California, Berkeley, Berkeley, California, United States of America

William G Scott

To whom correspondence should be addressed. E-mail: ychi@uky.edu (Y-IC); wgscott@chemistry.ucsc.edu (WGS); SHKim@cchem.berkeley.edu (SHK)

Affiliation Center for the Molecular Biology of RNA, Sinsheimer Laboratory, University of California at Santa Cruz, Santa Cruz, California, United States of America

Sung-Hou Kim

To whom correspondence should be addressed. E-mail: ychi@uky.edu (Y-IC); wgscott@chemistry.ucsc.edu (WGS); SHKim@cchem.berkeley.edu (SHK)

Affiliation Department of Chemistry, University of California, Berkeley, Berkeley, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

SHK conceived and designed the experiments. YIC performed the experiments. YIC and WGS analyzed the data. YIC, MM, and RK contributed reagents/materials/analysis tools. ML performed the ribozyme kinetic analyses. YIC and WGS authored the paper.