About the Authors

Thomas J Park

To whom correspondence should be addressed. E-mail: tpark@uic.edu (TJP); glewin@mdc-berlin.de (GRL)

Affiliation Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America

Ying Lu

Contributed equally to this work with: Ying Lu, René Jüttner, Ewan St. J Smith

Affiliation Department of Anesthesiology, University of Illinois at Chicago, Chicago, Illinois, United States of America

René Jüttner

Contributed equally to this work with: Ying Lu, René Jüttner, Ewan St. J Smith

Affiliation Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Ewan St. J Smith

Contributed equally to this work with: Ying Lu, René Jüttner, Ewan St. J Smith

Affiliation Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Jing Hu

Affiliation Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Antje Brand

Affiliation Laboratory of Integrative Neuroscience, Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States of America

Christiane Wetzel

Affiliation Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Nevena Milenkovic

Affiliation Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Bettina Erdmann

Affiliation Department of Electron Microscopy, Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Paul A Heppenstall

Affiliation Klinik für Anaesthesiologie und Operative Intensivmedizin, Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany

Charles E Laurito

Affiliation Department of Anesthesiology, University of Illinois at Chicago, Chicago, Illinois, United States of America

Steven P Wilson

Affiliation Department of Pharmacology, Physiology, and Neuroscience, University of South Carolina School of Medicine, Columbia, South Carolina, United States of America

Gary R Lewin

To whom correspondence should be addressed. E-mail: tpark@uic.edu (TJP); glewin@mdc-berlin.de (GRL)

Affiliation Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

TJP, YL, AB, NM, CEL, and GRL performed behavioral experiments. TJP, RJ, PAH, and GRL carried out electrophysiological experiments. ESJS carried out immunocytochemistry studies. JH and ESJS cultured mole-rat DRG neurons. JH performed calcium imaging. SPW provided engineered herpes virus. CW and BE performed and analyzed data from electron microscopy experiments. TJP and GRL conceived and planned experimental studies and wrote the paper.