About the Authors

Kwok Yeung Tsang

Contributed equally to this work with: Kwok Yeung Tsang, Danny Chan

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Danny Chan

Contributed equally to this work with: Kwok Yeung Tsang, Danny Chan

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Deborah Cheslett

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Wilson C. W Chan

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Chi Leong So

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Ian G Melhado

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Tori W. Y Chan

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Kin Ming Kwan

¤ Current address: Department of Biology, Chinese University of Hong Kong, Hong Kong, China

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Ernst B Hunziker

Affiliation ITI Research Institute for Dental and Skeletal Biology, University of Bern, Bern, Switzerland

Yoshihiko Yamada

Affiliation Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, Bethesda, Maryland, United States of America

John F Bateman

Affiliations Murdoch Childrens Research Institute, Royal Children's Hospital, Melbourne, Victoria, Australia , Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia

Kenneth M. C Cheung

Affiliation Department of Orthopaedics and Traumatology, University of Hong Kong, Pokfulam, Hong Kong, China

Kathryn S. E Cheah

To whom correspondence should be addressed. E-mail: hrmbdkc@hkusua.hku.hk

Affiliation Department of Biochemistry, University of Hong Kong, Pokfulam, Hong Kong, China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

K. Y. Tsang, D. Chan, K. M. Kwan, J. F. Bateman, K. M. C. Cheung, and K. S. E. Cheah conceived and designed the experiments. K. Y. Tsang, D. Chan, D. Cheslett, W. C. W. Chan, C. L. So, I. G. Melhado, T. W. Y. Chan, K. M. Kwan, and E. B, Hunziker performed the experiments. K. Y. Tsang, D. Chan, W. C. W. Chan, I. G. Melhado, E. B. Hunziker, and K. S. E. Cheah analyzed the data. Y. Yamada and J. F. Bateman contributed reagents/materials/analysis tools. K. Y. Tsang, D. Chan, and K. S. E. Cheah wrote the paper.