About the Authors

Eva M Schmid

Contributed equally to this work with: Eva M Schmid, Marijn G. J Ford

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Marijn G. J Ford

Contributed equally to this work with: Eva M Schmid, Marijn G. J Ford

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Anne Burtey

Affiliation Department of Infectious Diseases, Institut Cochin, Paris, France

Gerrit J. K Praefcke

Affiliation Center for Molecular Medicine Cologne, Institute for Genetics, University of Cologne, Köln, Germany

Sew-Yeu Peak-Chew

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Ian G Mills

Affiliation The Oncology Department, University of Cambridge Hutchison/MRC Cancer Research Centre, Cambridge, United Kingdom

Alexandre Benmerah

Affiliation Department of Infectious Diseases, Institut Cochin, Paris, France

Harvey T McMahon

To whom correspondence should be addressed. E-mail: hmm@mrc-lmb.cam.ac.uk

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

EMS, MGJF, AB, and HTM conceived and designed the experiments. AB performed the cell biology, MGJF the crystallography, and EMS the majority of the in vitro studies along with GJKP, SYPC, and IGM. EMS and HTM wrote the paper.