About the Authors

Yong-Xu Wang

Affiliation Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

Chun-Li Zhang

Affiliation Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

Ruth T Yu

Affiliation Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

Helen K Cho

Affiliation Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

Michael C Nelson

Affiliations Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America, Howard Hughes Medical Institute, La Jolla, California, United States of America

Corinne R Bayuga-Ocampo

Affiliation Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America

Jungyeob Ham

Affiliation Marine Biotechnology Laboratory, School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea

Heonjoong Kang

Affiliation Marine Biotechnology Laboratory, School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea

Ronald M Evans

To whom correspondence should be addressed. E-mail: evans@salk.edu

Affiliations Gene Expression Laboratory, Salk Institute, La Jolla, California, United States of America, Howard Hughes Medical Institute, La Jolla, California, United States of America

Competing Interests

The authors have declared that no conflicts of interest exist.

Author Contributions

YXW and RME conceived and designed the experiments. YXW, CLZ, RTY, MCN, and CRBO performed the experiments. YXW, CLZ, and RME analyzed the data. HKC, JH, and HK contributed reagents/materials/analysis tools. YXW and RME wrote the paper.