About the Authors

Derek P. Narendra

Affiliation Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Seok Min Jin

Affiliation Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Atsushi Tanaka

Affiliation Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Der-Fen Suen

Affiliation Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Clement A. Gautier

Affiliation Center for Neurologic Diseases, Brigham and Women's Hospital, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America

Jie Shen

Affiliation Center for Neurologic Diseases, Brigham and Women's Hospital, Program in Neuroscience, Harvard Medical School, Boston, Massachusetts, United States of America

Mark R. Cookson

Affiliation Cell Biology and Gene Expression Unit, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, Maryland, United States of America

Richard J. Youle

youler@ninds.nih.gov

Affiliation Biochemistry Section, Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

The author(s) have made the following declarations about their contributions: Conceived and designed the experiments: DPN SMJ AT DFS RJY. Performed the experiments: DPN SMJ AT. Analyzed the data: DPN SMJ AT MRC RJY. Contributed reagents/materials/analysis tools: CAG JS RJY. Wrote the paper: DPN RJY.