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Sex Pheromone in Lamprey Semen

July 9, 2019

Sex Pheromone in Lamprey Semen

Anne Scott, Zhe Zhang, Liang Jia, Richard Neubig, Weiming Li and co-workers find that male sea lampreys release via their ejaculates a highly specific and stimulatory sex pheromone, spermine, which activates a trace amine-associated receptor in the olfactory epithelium and attracts ready-to-mate females.

Image credit: USGS

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PLOS Biology's XV Collection

07/11/2019

Research Article

Calcium, Auxin and Root Growth

Ora Hazak, Elad Mamon, Shaul Yalovsky and colleagues show that an auxin-regulated calcium-dependent signal transducer, CMI1, regulates auxin responses and root development, providing a basis for cross talk between auxin and calcium signaling in plants.

Image credit: pbio.3000085

Calcium, Auxin and Root Growth

Recently Published Articles

Current Issue

Current Issue June 2019

07/09/2019

Research Article

New Antibiotics Inspired by Nature

Irène Nicolas, Valérie Bordeau, Brice Felden and co-authors used a naturally occurring bacterial toxin to inspire the design of novel cyclic heptapseudopeptide antibiotics with limited resistance; these new peptidomimetics are active against gram-negative and -positive multi-resistant ESKAPE pathogens.

Image credit: pbio.3000337

New Antibiotics Inspired by Nature

07/08/2019

Research Article

Candida's Hsp90 Interactome

A global view of the Hsp90 chaperone interactome in the fungal pathogen Candida albicans, by Teresa O’Meara, Leah Cowen and co-workers, reveals the dynamic role of Hsp90 in response to environmental perturbations, and highlights a novel connection between Hsp90 and the regulation of mRNA-associated protein granules.

Image credit: pbio.3000358

Candida's Hsp90 Interactome

07/11/2019

Research Article

Anterior Cingulate Cortex and Rule Maintenance

Liya Ma, Stefan Everling and colleagues show that reversible deactivation of the dorsal anterior cingulate cortex — an area of the cognitive control network — impairs rule maintenance but not rule switching per se, and disrupts task-related oscillatory activities in the dorsolateral prefrontal cortex — another area of the same network.

Anterior Cingulate Cortex and Rule Maintenance

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07/02/2019

Research Article

Solitariness and Aggression in Spiders

Behavioral experiments with the spider Agelena labyrinthica, coupled with computational modelling, by Violette Chiara, Felipe Ramon Portugal and Raphael Jeanson, show that an increase in mobility with age drives dispersal in gregarious spiderlings of a solitary species and that the subsequent social isolation triggers aggression.

Solitariness and Aggression in Spiders

Image credit: Flickr user Esin Üstün

07/01/2019

Community Page

The Human Brain Project

Katrin Amunts, Jan Bjaalie and co-authors present the Human Brain Project; a European Flagship project with a ten-year horizon aiming to understand the human brain and translate neuroscience knowledge into medicine and technology.

The Human Brain Project

Image credit: pbio.3000344

07/01/2019

Research Article

Triggering Salmonella's Needle 

Type III secretion machines evolved to inject bacterial effector proteins into eukaryotic cells. This study provides insights into the mechanism by which the contact signal is transduced to activate the protein secretion machine.

Triggering Salmonella's Needle 

Image credit: pbio.3000351

07/02/2019

Methods and Resources

Bone Genes from CRISPR Screening in Mice

Androgenetic haploid embryonic stem cells expressing Cas9 and a medium-scale sgRNA library provide a means to mutate genes at the organism level, here identifying Irx5 as a regulator of bone development.

Bone Genes from CRISPR Screening in Mice

Image credit: pbio.3000350

07/03/2019

Research Article

Human-Specific Expression Gradients in Visual Cortex

Expression of a subset of human genes forms two gradients that capture the processing hierarchy of visual cortex; these gradients emerge at different points during development and distinguish humans from other primates.

Human-Specific Expression Gradients in Visual Cortex

Image credit: pbio.3000362

07/03/2019

Methods and Resources

Single-Cell Transcriptome of the Human Fetal Retina

The transcriptomic landscape of the human fetal neural retina and retinal pigment epithelium reveals a tightly regulated spatiotemporal gene expression network of human retinal cells.

Single-Cell Transcriptome of the Human Fetal Retina

Image credit: pbio.3000365

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