Generation of synthetic tympanic membrane images: Development, human validation, and clinical implications of synthetic data

Krish Suresh; Michael S. Cohen; Christopher J. Hartnick; Ryan A. Bartholomew; Daniel J. Lee; Matthew G. Crowson

doi:10.1371/journal.pdig.0000202

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Open Access

Peer-reviewed

Research Article

Generation of synthetic tympanic membrane images: Development, human validation, and clinical implications of synthetic data

Krish Suresh ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Writing – original draft, Writing – review & editing

* E-mail: krish_suresh@meei.harvard.edu

Affiliations Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, United States of America, Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0001-7517-0280

⨯
Michael S. Cohen,

Roles Data curation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

Affiliations Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, United States of America, Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Christopher J. Hartnick,

Roles Data curation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

Affiliations Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, United States of America, Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Ryan A. Bartholomew,

Roles Methodology, Writing – review & editing

Affiliations Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, United States of America, Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Daniel J. Lee,

Roles Methodology, Supervision, Writing – review & editing

Affiliations Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, United States of America, Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Matthew G. Crowson

Roles Conceptualization, Data curation, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

Affiliations Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, United States of America, Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Generation of synthetic tympanic membrane images: Development, human validation, and clinical implications of synthetic data

Krish Suresh,
Michael S. Cohen,
Christopher J. Hartnick,
Ryan A. Bartholomew,
Daniel J. Lee,
Matthew G. Crowson

Published: February 24, 2023
https://doi.org/10.1371/journal.pdig.0000202

About the Authors

Krish Suresh

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Writing – original draft, Writing – review & editing

* E-mail: krish_suresh@meei.harvard.edu

Affiliations Department of Otolaryngology-Head & Neck Surgery, Massachusetts Eye & Ear, Boston, Massachusetts, United States of America, Department of Otolaryngology-Head & Neck Surgery, Harvard Medical School, Boston, Massachusetts, United States of America

https://orcid.org/0000-0001-7517-0280

Michael S. Cohen

Roles Data curation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

Christopher J. Hartnick

Roles Data curation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

Ryan A. Bartholomew

Roles Methodology, Writing – review & editing

Daniel J. Lee

Roles Methodology, Supervision, Writing – review & editing

Matthew G. Crowson

Roles Conceptualization, Data curation, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

Competing Interests

The authors have declared that no competing interests exist.

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Otolaryngological procedures
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Surveys
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Artificial membranes
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Deep learning
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Otorhinolaryngology
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Machine learning
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Radiology and imaging
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