May 2013

The early-medieval cemetery in Aschheim-Bajuwarenring, Upper Bavaria, Germany, consists of more than 430 graves with a large number of multiple burial sites (triple graves). Remains of two hand-holding women (green and blue) with a child in between (red), dated to the 6th century A. D. The agent of the plague, Yersinia pestis, was detected and characterized from tooth material of the blue colored skeleton. See Harbeck et al.

Image Credit: H.P. Volpert

Opinion

Behind Closed Membranes: The Secret Lives of Picornaviruses?

Alexsia L. Richards, William T. Jackson

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003262

Pearls

Experimental Evolution of Pathogenesis: “Patient” Research

Alexander W. Ensminger

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003340

Plant Virus Ecology

Marilyn J. Roossinck

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003304

The Secret Life of Viral Entry Glycoproteins: Moonlighting in Immune Evasion

Jonathan D. Cook, Jeffrey E. Lee

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003258

Polyphosphate and Its Diverse Functions in Host Cells and Pathogens

Silvia N. J. Moreno, Roberto Docampo

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003230

Reviews

Hemoglobinopathies: Slicing the Gordian Knot of Plasmodium falciparum Malaria Pathogenesis

Steve M. Taylor, Carla Cerami, Rick M. Fairhurst

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003327

Volatile Metabolites of Pathogens: A Systematic Review

Lieuwe D. J. Bos, Peter J. Sterk, Marcus J. Schultz

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003311

Research Articles

Membrane Assembly during the Infection Cycle of the Giant Mimivirus

Yael Mutsafi, Eyal Shimoni, Amir Shimon, Abraham Minsky

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003367

Murinization of Internalin Extends Its Receptor Repertoire, Altering Listeria monocytogenes Cell Tropism and Host Responses

Yu-Huan Tsai, Olivier Disson, Hélène Bierne, Marc Lecuit

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003381

Antibody Quality and Protection from Lethal Ebola Virus Challenge in Nonhuman Primates Immunized with Rabies Virus Based Bivalent Vaccine

Joseph E. Blaney, Andrea Marzi, Mallory Willet, Amy B. Papaneri, Christoph Wirblich, Friederike Feldmann, Michael Holbrook, Peter Jahrling, Heinz Feldmann, Matthias J. Schnell

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003389

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

Julie L. McAuley, Michelle D. Tate, Charley J. MacKenzie-Kludas, Anita Pinar, Weiguang Zeng, Andrea Stutz, Eicke Latz, Lorena E. Brown, Ashley Mansell

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003392

Identification of a Functional Type VI Secretion System in Campylobacter jejuni Conferring Capsule Polysaccharide Sensitive Cytotoxicity

Nancy M. C. Bleumink-Pluym, Lieke B. van Alphen, Lieneke I. Bouwman, Marc M. S. M. Wösten, Jos P. M. van Putten

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003393

Type I Interferon Programs Innate Myeloid Dynamics and Gene Expression in the Virally Infected Nervous System

Debasis Nayak, Kory R. Johnson, Sara Heydari, Theodore L. Roth, Bernd H. Zinselmeyer, Dorian B. McGavern

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003395

Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay

Gregory M. Laird, Evelyn E. Eisele, S. Alireza Rabi, Jun Lai, Stanley Chioma, Joel N. Blankson, Janet D. Siliciano, Robert F. Siliciano

PLOS Pathogens: published May 30, 2013 | https://doi.org/10.1371/journal.ppat.1003398

Prolonged Influenza Virus Shedding and Emergence of Antiviral Resistance in Immunocompromised Patients and Ferrets

Erhard van der Vries, Koert J. Stittelaar, Geert van Amerongen, Edwin J. B. Veldhuis Kroeze, Leon de Waal, Pieter L. A. Fraaij, Roland J. Meesters, Theo M. Luider, Bart van der Nagel, Birgit Koch, Arnold G. Vulto, Martin Schutten, Albert D. M. E. Osterhaus

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003343

Class A Scavenger Receptor 1 (MSR1) Restricts Hepatitis C Virus Replication by Mediating Toll-like Receptor 3 Recognition of Viral RNAs Produced in Neighboring Cells

Hiromichi Dansako, Daisuke Yamane, Christoph Welsch, David R. McGivern, Fengyu Hu, Nobuyuki Kato, Stanley M. Lemon

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003345

Global Organization of a Positive-strand RNA Virus Genome

Baodong Wu, Jörg Grigull, Moriam O. Ore, Sylvie Morin, K. Andrew White

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003363

Cis and Trans Acting Factors Involved in Human Cytomegalovirus Experimental and Natural Latent Infection of CD14 (+) Monocytes and CD34 (+) Cells

Cyprian C. Rossetto, Margaret Tarrant-Elorza, Gregory S. Pari

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003366

Pilus Phase Variation Switches Gonococcal Adherence to Invasion by Caveolin-1-Dependent Host Cell Signaling

Michaela Faulstich, Jan-Peter Böttcher, Thomas F. Meyer, Martin Fraunholz, Thomas Rudel

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003373

Asexual Populations of the Human Malaria Parasite, Plasmodium falciparum, Use a Two-Step Genomic Strategy to Acquire Accurate, Beneficial DNA Amplifications

Jennifer L. Guler, Daniel L. Freeman, Vida Ahyong, Rapatbhorn Patrapuvich, John White, Ramesh Gujjar, Margaret A. Phillips, Joseph DeRisi, Pradipsinh K. Rathod

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003375

Increase in Gut Microbiota after Immune Suppression in Baculovirus-infected Larvae

Agata K. Jakubowska, Heiko Vogel, Salvador Herrero

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003379

Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion

Stefanie Ameres, Josef Mautner, Fabian Schlott, Michael Neuenhahn, Dirk H. Busch, Bodo Plachter, Andreas Moosmann

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003383

Human Papillomavirus (HPV) Upregulates the Cellular Deubiquitinase UCHL1 to Suppress the Keratinocyte's Innate Immune Response

Rezaul Karim, Bart Tummers, Craig Meyers, Jennifer L. Biryukov, Samina Alam, Claude Backendorf, Veena Jha, Rienk Offringa, Gert-Jan B. van Ommen, Cornelis J. M. Melief, Daniele Guardavaccaro, Judith M. Boer, Sjoerd H. van der Burg

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003384

Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175

Edwin Chen, May M. Paing, Nichole Salinas, B. Kim Lee Sim, Niraj H. Tolia

PLOS Pathogens: published May 23, 2013 | https://doi.org/10.1371/journal.ppat.1003390

Saturated Very Long Chain Fatty Acids Are Required for the Production of Infectious Human Cytomegalovirus Progeny

Emre Koyuncu, John G. Purdy, Joshua D. Rabinowitz, Thomas Shenk

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003333

Abortive Lytic Reactivation of KSHV in CBF1/CSL Deficient Human B Cell Lines

Barbara A. Scholz, Marie L. Harth-Hertle, Georg Malterer, Juergen Haas, Joachim Ellwart, Thomas F. Schulz, Bettina Kempkes

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003336

Proving Lipid Rafts Exist: Membrane Domains in the Prokaryote Borrelia burgdorferi Have the Same Properties as Eukaryotic Lipid Rafts

Timothy J. LaRocca, Priyadarshini Pathak, Salvatore Chiantia, Alvaro Toledo, John R. Silvius, Jorge L. Benach, Erwin London

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003353

Rhesus Monkey Rhadinovirus Uses Eph Family Receptors for Entry into B Cells and Endothelial Cells but Not Fibroblasts

Alexander S. Hahn, Ronald C. Desrosiers

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003360

Uracil DNA Glycosylase Counteracts APOBEC3G-Induced Hypermutation of Hepatitis B Viral Genomes: Excision Repair of Covalently Closed Circular DNA

Kouichi Kitamura, Zhe Wang, Sajeda Chowdhury, Miyuki Simadu, Miki Koura, Masamichi Muramatsu

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003361

IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection

Iwana Schmitz, Christoph Schneider, Anja Fröhlich, Helge Frebel, Daniel Christ, Warren J. Leonard, Tim Sparwasser, Annette Oxenius, Stefan Freigang, Manfred Kopf

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003362

Structural Basis of HCV Neutralization by Human Monoclonal Antibodies Resistant to Viral Neutralization Escape

Thomas Krey, Annalisa Meola, Zhen-yong Keck, Laurence Damier-Piolle, Steven K. H. Foung, Felix A. Rey

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003364

Identification of Fibroblast Growth Factor Receptor 3 (FGFR3) as a Protein Receptor for Botulinum Neurotoxin Serotype A (BoNT/A)

Birgitte P. S. Jacky, Patton E. Garay, Jérôme Dupuy, Jeremy B. Nelson, Brian Cai, Yanira Molina, Joanne Wang, Lance E. Steward, Ron S. Broide, Joseph Francis, K. Roger Aoki, Raymond C. Stevens, Ester Fernández-Salas

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003369

Orthobunyavirus Ultrastructure and the Curious Tripodal Glycoprotein Spike

Thomas A. Bowden, David Bitto, Angela McLees, Christelle Yeromonahos, Richard M. Elliott, Juha T. Huiskonen

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003374

Dual Pili Post-translational Modifications Synergize to Mediate Meningococcal Adherence to Platelet Activating Factor Receptor on Human Airway Cells

Freda E. C. Jen, Matthew J. Warren, Benjamin L. Schulz, Peter M. Power, W. Edward Swords, Jeffery N. Weiser, Michael A. Apicella, Jennifer L. Edwards, Michael P. Jennings

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003377

The SNARE Protein Syp71 Is Essential for Turnip Mosaic Virus Infection by Mediating Fusion of Virus-Induced Vesicles with Chloroplasts

Taiyun Wei, Changwei Zhang, Xilin Hou, Hélène Sanfaçon, Aiming Wang

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003378

Structural Basis for Rab1 De-AMPylation by the Legionella pneumophila Effector SidD

Yang Chen, Igor Tascón, M. Ramona Neunuebel, Chiara Pallara, Jacqueline Brady, Lisa N. Kinch, Juan Fernández-Recio, Adriana L. Rojas, Matthias P. Machner, Aitor Hierro

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003382

Pasteurella Multocida Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gα_q/11 - p63RhoGEF - RhoA Axis

Peter Siegert, Gudula Schmidt, Panagiotis Papatheodorou, Thomas Wieland, Klaus Aktories, Joachim H. C. Orth

PLOS Pathogens: published May 16, 2013 | https://doi.org/10.1371/journal.ppat.1003385

Identification of Targets of CD8⁺ T Cell Responses to Malaria Liver Stages by Genome-wide Epitope Profiling

Julius Clemence R. Hafalla, Karolis Bauza, Johannes Friesen, Gloria Gonzalez-Aseguinolaza, Adrian V. S. Hill, Kai Matuschewski

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003303

Persistently Active Microbial Molecules Prolong Innate Immune Tolerance In Vivo

Mingfang Lu, Alan W. Varley, Robert S. Munford

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003339

Differences in Gastric Carcinoma Microenvironment Stratify According to EBV Infection Intensity: Implications for Possible Immune Adjuvant Therapy

Michael J. Strong, Guorong Xu, Joseph Coco, Carl Baribault, Dass S. Vinay, Michelle R. Lacey, Amy L. Strong, Teresa A. Lehman, Michael B. Seddon, Zhen Lin, Monica Concha, Melody Baddoo, MaryBeth Ferris, Kenneth F. Swan, Deborah E. Sullivan, Matthew E. Burow, Christopher M. Taylor, Erik K. Flemington

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003341

Malaria Parasite cGMP-dependent Protein Kinase Regulates Blood Stage Merozoite Secretory Organelle Discharge and Egress

Christine R. Collins, Fiona Hackett, Malcolm Strath, Maria Penzo, Chrislaine Withers-Martinez, David A. Baker, Michael J. Blackman

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003344

Recruitment of EB1, a Master Regulator of Microtubule Dynamics, to the Surface of the Theileria annulata Schizont

Kerry L. Woods, Romina Theiler, Marcus Mühlemann, Adrian Segiser, Sandra Huber, Hifzur R. Ansari, Arnab Pain, Dirk A. E. Dobbelaere

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003346

Challenges in Detecting HIV Persistence during Potentially Curative Interventions: A Study of the Berlin Patient

Steven A. Yukl, Eli Boritz, Michael Busch, Christopher Bentsen, Tae-Wook Chun, Daniel Douek, Evelyn Eisele, Ashley Haase, Ya-Chi Ho, Gero Hütter, J. Shawn Justement, Sheila Keating, Tzong-Hae Lee, Peilin Li, Danielle Murray, Sarah Palmer, Christopher Pilcher, Satish Pillai, Richard W. Price, Meghan Rothenberger, Timothy Schacker, Janet Siliciano, Robert Siliciano, Elizabeth Sinclair, Matt Strain, Joseph Wong, Douglas Richman, Steven G. Deeks

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003347

Mutualistic Polydnaviruses Share Essential Replication Gene Functions with Pathogenic Ancestors

Gaelen R. Burke, Sarah A. Thomas, Jai H. Eum, Michael R. Strand

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003348

NOD2-mediated Suppression of CD55 on Neutrophils Enhances C5a Generation During Polymicrobial Sepsis

Sae Jin Oh, Ji Hyung Kim, Doo Hyun Chung

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003351

Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity

Kevin R. McCarthy, Aaron G. Schmidt, Andrea Kirmaier, Allison L. Wyand, Ruchi M. Newman, Welkin E. Johnson

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003352

Antigenic Drift of the Pandemic 2009 A(H1N1) Influenza Virus in a Ferret Model

Teagan Guarnaccia, Louise A. Carolan, Sebastian Maurer-Stroh, Raphael T. C. Lee, Emma Job, Patrick C. Reading, Stephen Petrie, James M. McCaw, Jodie McVernon, Aeron C. Hurt, Anne Kelso, Jennifer Mosse, Ian G. Barr, Karen L. Laurie

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003354

Bile Acid Recognition by the Clostridium difficile Germinant Receptor, CspC, Is Important for Establishing Infection

Michael B. Francis, Charlotte A. Allen, Ritu Shrestha, Joseph A. Sorg

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003356

LAB/NTAL Facilitates Fungal/PAMP-induced IL-12 and IFN-γ Production by Repressing β-Catenin Activation in Dendritic Cells

Selinda J. Orr, Ashley R. Burg, Tim Chan, Laura Quigley, Gareth W. Jones, Jill W. Ford, Deborah Hodge, Catherine Razzook, Joseph Sarhan, Yava L. Jones, Gillian C. Whittaker, Kimberly C. Boelte, Lyudmila Lyakh, Marco Cardone, Geraldine M. O'Connor, Cuiyan Tan, Hongchuan Li, Stephen K. Anderson, Simon A. Jones, Weiguo Zhang, Philip R. Taylor, Giorgio Trinchieri, Daniel W. McVicar

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003357

Colocalization of Different Influenza Viral RNA Segments in the Cytoplasm before Viral Budding as Shown by Single-molecule Sensitivity FISH Analysis

Yi-ying Chou, Nicholas S. Heaton, Qinshan Gao, Peter Palese, Robert Singer, Timothée Lionnet

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003358

The Lipid Kinase Phosphatidylinositol-4 Kinase III Alpha Regulates the Phosphorylation Status of Hepatitis C Virus NS5A

Simon Reiss, Christian Harak, Inés Romero-Brey, Danijela Radujkovic, Rahel Klein, Alessia Ruggieri, Ilka Rebhan, Ralf Bartenschlager, Volker Lohmann

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003359

T-Cell Tropism of Simian Varicella Virus during Primary Infection

Werner J. D. Ouwendijk, Ravi Mahalingam, Rik L. de Swart, Bart L. Haagmans, Geert van Amerongen, Sarah Getu, Don Gilden, Albert D. M. E. Osterhaus, Georges M. G. M. Verjans

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003368

A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid

David C. Goldstone, Thomas G. Flower, Neil J. Ball, Marta Sanz-Ramos, Melvyn W. Yap, Roksana W. Ogrodowicz, Nicole Stanke, Juliane Reh, Dirk Lindemann, Jonathan P. Stoye, Ian A. Taylor

PLOS Pathogens: published May 9, 2013 | https://doi.org/10.1371/journal.ppat.1003376

The EBV Latent Antigen 3C Inhibits Apoptosis through Targeted Regulation of Interferon Regulatory Factors 4 and 8

Shuvomoy Banerjee, Jie Lu, Qiliang Cai, Abhik Saha, Hem Chandra Jha, Richard Kuo Dzeng, Erle S. Robertson

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003314

DRAM Triggers Lysosomal Membrane Permeabilization and Cell Death in CD4⁺ T Cells Infected with HIV

Mireille Laforge, Sophie Limou, Francis Harper, Nicoletta Casartelli, Vasco Rodrigues, Ricardo Silvestre, Houda Haloui, Jean-Francois Zagury, Anna Senik, Jerome Estaquier

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003328

A Nucleotide Sugar Transporter Involved in Glycosylation of the Toxoplasma Tissue Cyst Wall Is Required for Efficient Persistence of Bradyzoites

Carolina E. Caffaro, Anita A. Koshy, Li Liu, Gusti M. Zeiner, Carlos B. Hirschberg, John C. Boothroyd

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003331

An Extracellular Siderophore Is Required to Maintain the Mutualistic Interaction of Epichloë festucae with Lolium perenne

Linda J. Johnson, Albert Koulman, Michael Christensen, Geoffrey A. Lane, Karl Fraser, Natasha Forester, Richard D. Johnson, Gregory T. Bryan, Susanne Rasmussen

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003332

Recombinant Monovalent Llama-Derived Antibody Fragments (VHH) to Rotavirus VP6 Protect Neonatal Gnotobiotic Piglets against Human Rotavirus-Induced Diarrhea

Celina G. Vega, Marina Bok, Anastasia N. Vlasova, Kuldeep S. Chattha, Silvia Gómez-Sebastián, Carmen Nuñez, Carmen Alvarado, Rodrigo Lasa, José M. Escribano, Lorena L. Garaicoechea, Fernando Fernandez, Karin Bok, Andrés Wigdorovitz, Linda J. Saif, Viviana Parreño

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003334

The Production of Monokaryotic Hyphae by Cryptococcus neoformans Can Be Induced by High Temperature Arrest of the Cell Cycle and Is Independent of Same-Sex Mating

Jianmin Fu, Ian R. Morris, Brian L. Wickes

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003335

Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4⁺ T Lymphocytes

Uri R. Mbonye, Giridharan Gokulrangan, Manish Datt, Curtis Dobrowolski, Maxwell Cooper, Mark R. Chance, Jonathan Karn

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003338

Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans

Jean-Philippe Julien, Devin Sok, Reza Khayat, Jeong Hyun Lee, Katie J. Doores, Laura M. Walker, Alejandra Ramos, Devan C. Diwanji, Robert Pejchal, Albert Cupo, Umesh Katpally, Rafael S. Depetris, Robyn L. Stanfield, Ryan McBride, Andre J. Marozsan, James C. Paulson, Rogier W. Sanders, John P. Moore, Dennis R. Burton, Pascal Poignard, Andrew B. Ward, Ian A. Wilson

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003342

Yersinia pestis DNA from Skeletal Remains from the 6^th Century AD Reveals Insights into Justinianic Plague

Michaela Harbeck, Lisa Seifert, Stephanie Hänsch, David M. Wagner, Dawn Birdsell, Katy L. Parise, Ingrid Wiechmann, Gisela Grupe, Astrid Thomas, Paul Keim, Lothar Zöller, Barbara Bramanti, Julia M. Riehm, Holger C. Scholz

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003349

Hepatitis C Virus p7 is Critical for Capsid Assembly and Envelopment

Juliane Gentzsch, Christiane Brohm, Eike Steinmann, Martina Friesland, Nicolas Menzel, Gabrielle Vieyres, Paula Monteiro Perin, Anne Frentzen, Lars Kaderali, Thomas Pietschmann

PLOS Pathogens: published May 2, 2013 | https://doi.org/10.1371/journal.ppat.1003355

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The plague bacterium Yersinia pestis in skeletal remains of the 6th century A.D.

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**The plague bacterium Yersinia pestis in skeletal remains of the 6th century A.D.**