Two colonies of C. albicans grown for 19 days on GM-bromocresol green agar, pH 4. The fungus actively raises the pH of its surrounding environment. This alkalinization converts the normally dull green medium to a strong teal blue, whilst the filamentous fringes of the colonies (white) extend away from each other (see Mayer et al., doi: 10.1371/journal.ppat.1002592).
Image Credit: François Mayer, Bernhard Hube, and Duncan Wilson, Department of Microbial Pathogenicity Mechanisms, Hans-Knoell-Institute
Opinion
An Entomopathogenic Nematode by Any Other Name
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002527
Pearls
A Foot in the Door for Dermatophyte Research
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002564
Mutation and Selection of Prions
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002582
Sleeping with the Enemy: How Intracellular Pathogens Cope with a Macrophage Lifestyle
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002551
New Insights into Blastocystis spp.: A Potential Link with Irritable Bowel Syndrome
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002545
Taste for Blood: Hemoglobin as a Nutrient Source for Pathogens
PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002535
Indifferent, Affectionate, or Deceitful: Lifestyles and Secretomes of Fungi
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002515
Research Articles
In Situ Microscopy Analysis Reveals Local Innate Immune Response Developed around Brucella Infected Cells in Resistant and Susceptible Mice
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002575
C. elegans Germ Cells Show Temperature and Age-Dependent Expression of Cer1, a Gypsy/Ty3-Related Retrotransposon
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002591
A Novel Mouse Model of Schistosoma haematobium Egg-Induced Immunopathology
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002605
A Cytoplasmic Tail Determinant in HIV-1 Vpu Mediates Targeting of Tetherin for Endosomal Degradation and Counteracts Interferon-Induced Restriction
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002609
HIV-1 Superinfection in Women Broadens and Strengthens the Neutralizing Antibody Response
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002611
Virulence Regulator EspR of Mycobacterium tuberculosis Is a Nucleoid-Associated Protein
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002621
Dengue Virus Infection of the Aedes aegypti Salivary Gland and Chemosensory Apparatus Induces Genes that Modulate Infection and Blood-Feeding Behavior
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002631
Shiga Toxin 1 Induces on Lipopolysaccharide-Treated Astrocytes the Release of Tumor Necrosis Factor-alpha that Alter Brain-Like Endothelium Integrity
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002632
Anthrax Lethal Factor Cleavage of Nlrp1 Is Required for Activation of the Inflammasome
PLOS Pathogens: published March 29, 2012 | https://doi.org/10.1371/journal.ppat.1002638
Comparative Genomics of the Apicomplexan Parasites Toxoplasma gondii and Neospora caninum: Coccidia Differing in Host Range and Transmission Strategy
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002567
Additive Function of Vibrio vulnificus MARTXVv and VvhA Cytolysins Promotes Rapid Growth and Epithelial Tissue Necrosis During Intestinal Infection
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002581
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PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002584
Mannose Binding Lectin Is Required for Alphavirus-Induced Arthritis/Myositis
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002586
A Single Nucleotide Polymorphism in Tetherin Promotes Retrovirus Restriction In Vivo
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002596
The Core Protein of Classical Swine Fever Virus Is Dispensable for Virus Propagation In Vitro
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002598
Direct Recognition of Fusobacterium nucleatum by the NK Cell Natural Cytotoxicity Receptor NKp46 Aggravates Periodontal Disease
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002601
Peptidoglycan-Modifying Enzyme Pgp1 Is Required for Helical Cell Shape and Pathogenicity Traits in Campylobacter jejuni
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002602
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Multiple Peptidoglycan Modification Networks Modulate Helicobacter pylori's Cell Shape, Motility, and Colonization Potential
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002603
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Chemoenzymatic Site-Specific Labeling of Influenza Glycoproteins as a Tool to Observe Virus Budding in Real Time
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002604
Inactivation of Staphylococcal Phenol Soluble Modulins by Serum Lipoprotein Particles
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002606
Induced Release of a Plant-Defense Volatile ‘Deceptively’ Attracts Insect Vectors to Plants Infected with a Bacterial Pathogen
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002610
Thriving under Stress: Selective Translation of HIV-1 Structural Protein mRNA during Vpr-Mediated Impairment of eIF4E Translation Activity
PLOS Pathogens: published March 22, 2012 | https://doi.org/10.1371/journal.ppat.1002612
A Peptidoglycan Fragment Triggers β-lactam Resistance in Bacillus licheniformis
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002571
E2F1 Mediated Apoptosis Induced by the DNA Damage Response Is Blocked by EBV Nuclear Antigen 3C in Lymphoblastoid Cells
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002573
Stage Specific Assessment of Candida albicans Phagocytosis by Macrophages Identifies Cell Wall Composition and Morphogenesis as Key Determinants
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002578
HMOX1 Gene Promoter Alleles and High HO-1 Levels Are Associated with Severe Malaria in Gambian Children
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002579
Preferential Entry of Botulinum Neurotoxin A Hc Domain through Intestinal Crypt Cells and Targeting to Cholinergic Neurons of the Mouse Intestine
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002583
Nasal Acai Polysaccharides Potentiate Innate Immunity to Protect against Pulmonary Francisella tularensis and Burkholderia pseudomallei Infections
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002587
The Novel Candida albicans Transporter Dur31 Is a Multi-Stage Pathogenicity Factor
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002592
Inflammation and Disintegration of Intestinal Villi in an Experimental Model for Vibrio parahaemolyticus-Induced Diarrhea
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002593
TGF-β1 Down-Regulation of NKG2D/DAP10 and 2B4/SAP Expression on Human NK Cells Contributes to HBV Persistence
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002594
Molecular Determinants of Resistance Activation and Suppression by Phytophthora infestans Effector IPI-O
PLOS Pathogens: published March 15, 2012 | https://doi.org/10.1371/journal.ppat.1002595
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PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002529
Differential Function of Lip Residues in the Mechanism and Biology of an Anthrax Hemophore
PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002559
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PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002565
Influenza A Virus Infection of Human Primary Dendritic Cells Impairs Their Ability to Cross-Present Antigen to CD8 T Cells
PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002572
Capsule Type of Streptococcus pneumoniae Determines Growth Phenotype
PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002574
Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity
PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002576
Human Cytomegalovirus Clinical Strain-Specific microRNA miR-UL148D Targets the Human Chemokine RANTES during Infection
PLOS Pathogens: published March 8, 2012 | https://doi.org/10.1371/journal.ppat.1002577
Phosphorylcholine Allows for Evasion of Bactericidal Antibody by Haemophilus influenzae
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002521
Structural Insights into a Unique Legionella pneumophila Effector LidA Recognizing Both GDP and GTP Bound Rab1 in Their Active State
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002528
PK-sensitive PrPSc Is Infectious and Shares Basic Structural Features with PK-resistant PrPSc
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002547
Fungal-Induced Cell Cycle Impairment, Chromosome Instability and Apoptosis via Differential Activation of NF-κB
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002555
Critical Role of Perforin-dependent CD8+ T Cell Immunity for Rapid Protective Vaccination in a Murine Model for Human Smallpox
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002557
LEDGF/p75-Independent HIV-1 Replication Demonstrates a Role for HRP-2 and Remains Sensitive to Inhibition by LEDGINs
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002558
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Redundant Notch1 and Notch2 Signaling Is Necessary for IFNγ Secretion by T Helper 1 Cells During Infection with Leishmania major
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Visualization and Measurement of ATP Levels in Living Cells Replicating Hepatitis C Virus Genome RNA
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002561
Identification of O-mannosylated Virulence Factors in Ustilago maydis
PLOS Pathogens: published March 1, 2012 | https://doi.org/10.1371/journal.ppat.1002563
Kaposi's Sarcoma Herpesvirus Upregulates Aurora A Expression to Promote p53 Phosphorylation and Ubiquitylation
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A20 (Tnfaip3) Deficiency in Myeloid Cells Protects against Influenza A Virus Infection
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