Fluorescence micrograph of an NIH3T3 cell expressing the phosphatidylinositol-4,5-bisphosphate reporter PLCδ-PH-GFP (green) after infection with Salmonella typhimurium engineered to deliver augmented levels of SipC (see Cain et al., e1000037). Cells are co-stained with Texas Red-conjugated phalloidin (red) and DAPI (blue) to visualize F-actin and cell nuclei and bacteria, respectively.
Image Credit: Image generated by Robert Cain.Opinion
Pathogen Discovery
PLOS Pathogens: published April 25, 2008 | https://doi.org/10.1371/journal.ppat.1000002
Research Articles
A Novel Secretion Pathway of Salmonella enterica Acts as an Antivirulence Modulator during Salmonellosis
PLOS Pathogens: published April 4, 2008 | https://doi.org/10.1371/journal.ppat.1000036
Deciphering Interplay between Salmonella Invasion Effectors
PLOS Pathogens: published April 4, 2008 | https://doi.org/10.1371/journal.ppat.1000037
Tobacco mosaic virus Movement Protein Enhances the Spread of RNA Silencing
PLOS Pathogens: published April 4, 2008 | https://doi.org/10.1371/journal.ppat.1000038
The MHV68 M2 Protein Drives IL-10 Dependent B Cell Proliferation and Differentiation
PLOS Pathogens: published April 4, 2008 | https://doi.org/10.1371/journal.ppat.1000039
Stimulation of Chitin Synthesis Rescues Candida albicans from Echinocandins
PLOS Pathogens: published April 4, 2008 | https://doi.org/10.1371/journal.ppat.1000040
Tentative T Cells: Memory Cells Are Quick to Respond, but Slow to Divide
PLOS Pathogens: published April 11, 2008 | https://doi.org/10.1371/journal.ppat.1000041
An Unbiased Systems Genetics Approach to Mapping Genetic Loci Modulating Susceptibility to Severe Streptococcal Sepsis
PLOS Pathogens: published April 18, 2008 | https://doi.org/10.1371/journal.ppat.1000042
Human-Like Receptor Specificity Does Not Affect the Neuraminidase-Inhibitor Susceptibility of H5N1 Influenza Viruses
PLOS Pathogens: published April 11, 2008 | https://doi.org/10.1371/journal.ppat.1000043
Histoplasma Requires SID1, a Member of an Iron-Regulated Siderophore Gene Cluster, for Host Colonization
PLOS Pathogens: published April 11, 2008 | https://doi.org/10.1371/journal.ppat.1000044
Molecular and Cellular Basis of Microvascular Perfusion Deficits Induced by Clostridium perfringens and Clostridium septicum
PLOS Pathogens: published April 11, 2008 | https://doi.org/10.1371/journal.ppat.1000045
Chapare Virus, a Newly Discovered Arenavirus Isolated from a Fatal Hemorrhagic Fever Case in Bolivia
PLOS Pathogens: published April 18, 2008 | https://doi.org/10.1371/journal.ppat.1000047
Identification of a Bacterial-Like HslVU Protease in the Mitochondria of Trypanosoma brucei and Its Role in Mitochondrial DNA Replication
PLOS Pathogens: published April 18, 2008 | https://doi.org/10.1371/journal.ppat.1000048
DC-SIGN and CD150 Have Distinct Roles in Transmission of Measles Virus from Dendritic Cells to T-Lymphocytes
PLOS Pathogens: published April 18, 2008 | https://doi.org/10.1371/journal.ppat.1000049
Transmission Pathways of Foot-and-Mouth Disease Virus in the United Kingdom in 2007
PLOS Pathogens: published April 18, 2008 | https://doi.org/10.1371/journal.ppat.1000050
agr-Mediated Dispersal of Staphylococcus aureus Biofilms
PLOS Pathogens: published April 25, 2008 | https://doi.org/10.1371/journal.ppat.1000052
HDP—A Novel Heme Detoxification Protein from the Malaria Parasite
PLOS Pathogens: published April 25, 2008 | https://doi.org/10.1371/journal.ppat.1000053