Microbial Contamination in Next Generation Sequencing: Implications for Sequence-Based Analysis of Clinical Samples

Michael J. Strong, Guorong Xu, Lisa Morici, Sandra Splinter Bon-Durant, Melody Baddoo, Zhen Lin, Claire Fewell, Christopher M. Taylor, Erik K. Flemington

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004437

Inhibitors of Peptidyl Proline Isomerases As Antivirals in Hepatitis C and Other Viruses

Rob Striker, Andrew Mehle

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004428

Genomic Insights into the Fungal Pathogens of the Genus Pneumocystis: Obligate Biotrophs of Humans and Other Mammals

Philippe M. Hauser

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004425

War and Infectious Diseases: Challenges of the Syrian Civil War

Sima L. Sharara, Souha S. Kanj

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004438

The Skin Microbiome: A Focus on Pathogens and Their Association with Skin Disease

Keisha Findley, Elizabeth A. Grice

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004436

Multiple Roles of the Cytoskeleton in Bacterial Autophagy

Serge Mostowy

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004409

Peculiarities of Prion Diseases

Walker S. Jackson, Clemens Krost

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004451

The Evolution and Genetics of Virus Host Shifts

Ben Longdon, Michael A. Brockhurst, Colin A. Russell, John J. Welch, Francis M. Jiggins

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004395

A Conserved Peptide Pattern from a Widespread Microbial Virulence Factor Triggers Pattern-Induced Immunity in Arabidopsis

Hannah Böhm, Isabell Albert, Stan Oome, Tom M. Raaymakers, Guido Van den Ackerveken, Thorsten Nürnberger

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004491

The Pseudomonas aeruginosa Type III Translocon Is Required for Biofilm Formation at the Epithelial Barrier

Cindy S. Tran, Stephanie M. Rangel, Henrik Almblad, Arlinet Kierbel, Michael Givskov, Tim Tolker-Nielsen, Alan R. Hauser, Joanne N. Engel

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004479

The Relationship between Host Lifespan and Pathogen Reservoir Potential: An Analysis in the System Arabidopsis thaliana-Cucumber mosaic virus

Jean Michel Hily, Adrián García, Arancha Moreno, María Plaza, Mark D. Wilkinson, Alberto Fereres, Aurora Fraile, Fernando García-Arenal

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004492

Programmed Ribosomal Frameshift Alters Expression of West Nile Virus Genes and Facilitates Virus Replication in Birds and Mosquitoes

Ezequiel Balmori Melian, Sonja Hall-Mendelin, Fangyao Du, Nick Owens, Angela M. Bosco-Lauth, Tomoko Nagasaki, Stephen Rudd, Aaron C. Brault, Richard A. Bowen, Roy A. Hall, Andrew F. van den Hurk, Alexander A. Khromykh

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004447

Co-dependence of HTLV-1 p12 and p8 Functions in Virus Persistence

Cynthia A. Pise-Masison, Maria Fernanda de Castro-Amarante, Yoshimi Enose-Akahata, R. Cody Buchmann, Claudio Fenizia, Robyn Washington Parks, Dustin Edwards, Martina Fiocchi, Luiz Carlos Alcantara Jr, Izabela Bialuk, Jhanelle Graham, Jean-Claude Walser, Katherine McKinnon, Bernardo Galvão-Castro, Antoine Gessain, David Venzon, Steven Jacobson, Genoveffa Franchini

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004454

A Gatekeeper Chaperone Complex Directs Translocator Secretion during Type Three Secretion

Tara L. Archuleta, Benjamin W. Spiller

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004498

IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

Silvia Moretti, Silvia Bozza, Vasilis Oikonomou, Giorgia Renga, Andrea Casagrande, Rossana G. Iannitti, Matteo Puccetti, Cecilia Garlanda, Soohyun Kim, Suzhao Li, Frank L. van de Veerdonk, Charles A. Dinarello, Luigina Romani

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004462

Silencing by H-NS Potentiated the Evolution of Salmonella

Sabrina S. Ali, Jeremy Soo, Chitong Rao, Andrea S. Leung, David Hon-Man Ngai, Alexander W. Ensminger, William Wiley Navarre

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004500

Unravelling Human Trypanotolerance: IL8 is Associated with Infection Control whereas IL10 and TNFα Are Associated with Subsequent Disease Development

Hamidou Ilboudo, Rachel Bras-Gonçalves, Mamadou Camara, Laurence Flori, Oumou Camara, Hassane Sakande, Mamadou Leno, Elodie Petitdidier, Vincent Jamonneau, Bruno Bucheton

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004469

ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

Dawoon Chung, Bridget M. Barker, Charles C. Carey, Brittney Merriman, Ernst R. Werner, Beatrix E. Lechner, Sourabh Dhingra, Chao Cheng, Wenjie Xu, Sara J. Blosser, Kengo Morohashi, Aurélien Mazurie, Thomas K. Mitchell, Hubertus Haas, Aaron P. Mitchell, Robert A. Cramer

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004487

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Host-Specific Parvovirus Evolution in Nature Is Recapitulated by In Vitro Adaptation to Different Carnivore Species

Andrew B. Allison, Dennis J. Kohler, Alicia Ortega, Elizabeth A. Hoover, Daniel M. Grove, Edward C. Holmes, Colin R. Parrish

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004475

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1. Correction: Host-Specific Parvovirus Evolution in Nature Is Recapitulated by In Vitro Adaptation to Different Carnivore Species

Acidification Activates Toxoplasma gondii Motility and Egress by Enhancing Protein Secretion and Cytolytic Activity

Marijo S. Roiko, Nadezhda Svezhova, Vern B. Carruthers

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004488

Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner

Christine Burkard, Monique H. Verheije, Oliver Wicht, Sander I. van Kasteren, Frank J. van Kuppeveld, Bart L. Haagmans, Lucas Pelkmans, Peter J. M. Rottier, Berend Jan Bosch, Cornelis A. M. de Haan

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004502

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1. Correction: Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner

IFI16 Restricts HSV-1 Replication by Accumulating on the HSV-1 Genome, Repressing HSV-1 Gene Expression, and Directly or Indirectly Modulating Histone Modifications

Karen E. Johnson, Virginie Bottero, Stephanie Flaherty, Sujoy Dutta, Vivek Vikram Singh, Bala Chandran

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004503

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The Epithelial αvβ3-Integrin Boosts the MYD88-Dependent TLR2 Signaling in Response to Viral and Bacterial Components

Tatiana Gianni, Gabriella Campadelli-Fiume

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004477

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Activation of HIV Transcription with Short-Course Vorinostat in HIV-Infected Patients on Suppressive Antiretroviral Therapy

Julian H. Elliott, Fiona Wightman, Ajantha Solomon, Khader Ghneim, Jeffrey Ahlers, Mark J. Cameron, Miranda Z. Smith, Tim Spelman, James McMahon, Pushparaj Velayudham, Gregor Brown, Janine Roney, Jo Watson, Miles H. Prince, Jennifer F. Hoy, Nicolas Chomont, Rémi Fromentin, Francesco A. Procopio, Joumana Zeidan, Sarah Palmer, Lina Odevall, Ricky W. Johnstone, Ben P. Martin, Elizabeth Sinclair, Steven G. Deeks, Daria J. Hazuda, Paul U. Cameron, Rafick-Pierre Sékaly, Sharon R. Lewin

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004473

Restriction of Francisella novicida Genetic Diversity during Infection of the Vector Midgut

Kathryn E. Reif, Guy H. Palmer, David W. Crowder, Massaro W. Ueti, Susan M. Noh

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004499

Aminoterminal Amphipathic α-Helix AH1 of Hepatitis C Virus Nonstructural Protein 4B Possesses a Dual Role in RNA Replication and Virus Production

Jérôme Gouttenoire, Roland Montserret, David Paul, Rosa Castillo, Simon Meister, Ralf Bartenschlager, François Penin, Darius Moradpour

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004501

The Plasmodesmal Protein PDLP1 Localises to Haustoria-Associated Membranes during Downy Mildew Infection and Regulates Callose Deposition

Marie-Cécile Caillaud, Lennart Wirthmueller, Jan Sklenar, Kim Findlay, Sophie J. M. Piquerez, Alexandra M. E. Jones, Silke Robatzek, Jonathan D. G. Jones, Christine Faulkner

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004496

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Plasticity between MyoC- and MyoA-Glideosomes: An Example of Functional Compensation in Toxoplasma gondii Invasion

Karine Frénal, Jean-Baptiste Marq, Damien Jacot, Valérie Polonais, Dominique Soldati-Favre

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004504

PUL21a-Cyclin A2 Interaction is Required to Protect Human Cytomegalovirus-Infected Cells from the Deleterious Consequences of Mitotic Entry

Martin Eifler, Ralf Uecker, Henry Weisbach, Boris Bogdanow, Ellen Richter, Lydia König, Barbara Vetter, Tihana Lenac-Rovis, Stipan Jonjic, Heidemarie Neitzel, Christian Hagemeier, Lüder Wiebusch

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004514

Retromer Regulates HIV-1 Envelope Glycoprotein Trafficking and Incorporation into Virions

Elisabetta Groppelli, Alice C. Len, Luke A. Granger, Clare Jolly

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004518

Crystal Structure of Cytomegalovirus IE1 Protein Reveals Targeting of TRIM Family Member PML via Coiled-Coil Interactions

Myriam Scherer, Stefan Klingl, Madhumati Sevvana, Victoria Otto, Eva-Maria Schilling, Joachim D. Stump, Regina Müller, Nina Reuter, Heinrich Sticht, Yves A. Muller, Thomas Stamminger

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004512

Succinate Dehydrogenase is the Regulator of Respiration in Mycobacterium tuberculosis

Travis Hartman, Brian Weinrick, Catherine Vilchèze, Michael Berney, Joanne Tufariello, Gregory M. Cook, William R. Jacobs Jr.

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004510

Dysregulated B Cell Expression of RANKL and OPG Correlates with Loss of Bone Mineral Density in HIV Infection

Kehmia Titanji, Aswani Vunnava, Anandi N. Sheth, Cecile Delille, Jeffrey L. Lennox, Sara E. Sanford, Antonina Foster, Andrea Knezevic, Kirk A. Easley, M. Neale Weitzmann, Ighovwerha Ofotokun

PLOS Pathogens: published November 13, 2014 | https://doi.org/10.1371/journal.ppat.1004497

Genetics, Receptor Binding Property, and Transmissibility in Mammals of Naturally Isolated H9N2 Avian Influenza Viruses

Xuyong Li, Jianzhong Shi, Jing Guo, Guohua Deng, Qianyi Zhang, Jinliang Wang, Xijun He, Kaicheng Wang, Jiming Chen, Yuanyuan Li, Jun Fan, Huiui Kong, Chunyang Gu, Yuantao Guan, Yasuo Suzuki, Yoshihiro Kawaoka, Liling Liu, Yongping Jiang, Guobin Tian, Yanbing Li, Zhigao Bu, Hualan Chen

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004508

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Shed GP of Ebola Virus Triggers Immune Activation and Increased Vascular Permeability

Beatriz Escudero-Pérez, Valentina A. Volchkova, Olga Dolnik, Philip Lawrence, Viktor E. Volchkov

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004509

Human Cytomegalovirus Vaccine Based on the Envelope gH/gL Pentamer Complex

Felix Wussow, Flavia Chiuppesi, Joy Martinez, John Campo, Erica Johnson, Christin Flechsig, Maegan Newell, Elaine Tran, Jose Ortiz, Corinna La Rosa, Andreas Herrmann, Jeff Longmate, Rana Chakraborty, Peter A. Barry, Don J. Diamond

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004524

NK Cell Activation in Human Hantavirus Infection Explained by Virus-Induced IL-15/IL15Rα Expression

Monika Braun, Niklas K. Björkström, Shawon Gupta, Karin Sundström, Clas Ahlm, Jonas Klingström, Hans-Gustaf Ljunggren

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004521

Structure and Specificity of the Bacterial Cysteine Methyltransferase Effector NleE Suggests a Novel Substrate in Human DNA Repair Pathway

Qing Yao, Li Zhang, Xiaobo Wan, Jing Chen, Liyan Hu, Xiaojun Ding, Lin Li, Jayashree Karar, Hongzhuang Peng, She Chen, Niu Huang, Frank J. Rauscher III, Feng Shao

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004522

GAPDH-A Recruits a Plant Virus Movement Protein to Cortical Virus Replication Complexes to Facilitate Viral Cell-to-Cell Movement

Masanori Kaido, Kazutomo Abe, Akira Mine, Kiwamu Hyodo, Takako Taniguchi, Hisaaki Taniguchi, Kazuyuki Mise, Tetsuro Okuno

PLOS Pathogens: published November 20, 2014 | https://doi.org/10.1371/journal.ppat.1004505

Correction: Opposing Regulation of PROX1 by Interleukin-3 Receptor and NOTCH Directs Differential Host Cell Fate Reprogramming by Kaposi Sarcoma Herpes Virus

The PLOS Pathogens Staff

PLOS Pathogens: published November 6, 2014 | https://doi.org/10.1371/journal.ppat.1004544

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Correction: Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes

The PLOS Pathogens Staff

PLOS Pathogens: published November 21, 2014 | https://doi.org/10.1371/journal.ppat.1004572

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Correction: ChIP-seq and In Vivo Transcriptome Analyses of the Aspergillus fumigatus SREBP SrbA Reveals a New Regulator of the Fungal Hypoxia Response and Virulence

The PLOS Pathogens Staff

PLOS Pathogens: published November 24, 2014 | https://doi.org/10.1371/journal.ppat.1004576

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