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A green fluorescent protein (GFP)-labeled strain of the coral pathogen Vibrio coralliilyticus.
Coral diseases have fundamentally altered Caribbean coral reef ecosystems and pose a growing threat to Indo-Pacific reefs, yet little is known about the etiologies and pathogeneses of many of these diseases. Coral disease researchers require the development of tools to detect and quantify putative pathogens in both controlled laboratory experiments and environmentally derived samples. Novel tools, such as this GFP-labeled strain of the coral pathogen V. coralliilyticus (shown here as a green aggregate), are currently being used to clarify the role of individual microbes in the onset and spread of coral disease lesions (see Pollock et al., doi: 10.1371/journal.ppat.1002183).
Image Credit: F. Joseph Pollock, James Cook University and the Australian Institute of Marine Science, Australia
Opinion
Defining Emerging Roles for NF-κB in Antivirus Responses: Revisiting the Interferon-β Enhanceosome Paradigm
PLOS Pathogens: published October 13, 2011 | https://doi.org/10.1371/journal.ppat.1002165
Pearls
Quorum Sensing in Fungi: Q&A
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002301
Review
The Urgent Need for Robust Coral Disease Diagnostics
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002183
Research Articles
Frequent and Recent Human Acquisition of Simian Foamy Viruses Through Apes' Bites in Central Africa
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002306
Non-Hematopoietic Cells in Lymph Nodes Drive Memory CD8 T Cell Inflation during Murine Cytomegalovirus Infection
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002313
Deep Molecular Characterization of HIV-1 Dynamics under Suppressive HAART
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002314
Histone Deacetylase 8 Is Required for Centrosome Cohesion and Influenza A Virus Entry
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002316
Leishmania Mitochondrial Peroxiredoxin Plays a Crucial Peroxidase-Unrelated Role during Infection: Insight into Its Novel Chaperone Activity
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002325
Tubule-Guided Cell-to-Cell Movement of a Plant Virus Requires Class XI Myosin Motors
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002327
The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002331
Herpesvirus Telomerase RNA (vTR) with a Mutated Template Sequence Abrogates Herpesvirus-Induced Lymphomagenesis
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002333
RNA Polymerase II Stalling Promotes Nucleosome Occlusion and pTEFb Recruitment to Drive Immortalization by Epstein-Barr Virus
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002334
IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic Entry
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002337
Coordinated Destruction of Cellular Messages in Translation Complexes by the Gammaherpesvirus Host Shutoff Factor and the Mammalian Exonuclease Xrn1
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002339
Targeting Cattle-Borne Zoonoses and Cattle Pathogens Using a Novel Trypanosomatid-Based Delivery System
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002340
Signal Transduction through CsrRS Confers an Invasive Phenotype in Group A Streptococcus
PLOS Pathogens: published October 27, 2011 | https://doi.org/10.1371/journal.ppat.1002361
Structural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA Inhibition
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002249
An Integrated Approach to Elucidate the Intra-Viral and Viral-Cellular Protein Interaction Networks of a Gamma-Herpesvirus
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002297
Fitness Landscape of Antibiotic Tolerance in Pseudomonas aeruginosa Biofilms
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002298
Trafficking of Hepatitis C Virus Core Protein during Virus Particle Assembly
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002302
Discovery of an Ebolavirus-Like Filovirus in Europe
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002304
Preventing Staphylococcus aureus Sepsis through the Inhibition of Its Agglutination in Blood
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002307
Soluble Rhesus Lymphocryptovirus gp350 Protects against Infection and Reduces Viral Loads in Animals that Become Infected with Virus after Challenge
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002308
The Mouse IAPE Endogenous Retrovirus Can Infect Cells through Any of the Five GPI-Anchored EphrinA Proteins
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002309
A Phenome-Based Functional Analysis of Transcription Factors in the Cereal Head Blight Fungus, Fusarium graminearum
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002310
Distinct Single Amino Acid Replacements in the Control of Virulence Regulator Protein Differentially Impact Streptococcal Pathogenesis
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002311
Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Regulates Cell Stress Response and Apoptosis
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002315
ISG15 Is Critical in the Control of Chikungunya Virus Infection Independent of UbE1L Mediated Conjugation
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002322
Novel Mouse Xenograft Models Reveal a Critical Role of CD4+ T Cells in the Proliferation of EBV-Infected T and NK Cells
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002326
Exhausted Cytotoxic Control of Epstein-Barr Virus in Human Lupus
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002328
Suppression of Methylation-Mediated Transcriptional Gene Silencing by βC1-SAHH Protein Interaction during Geminivirus-Betasatellite Infection
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002329
HacA-Independent Functions of the ER Stress Sensor IreA Synergize with the Canonical UPR to Influence Virulence Traits in Aspergillus fumigatus
PLOS Pathogens: published October 20, 2011 | https://doi.org/10.1371/journal.ppat.1002330
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A Novel Core Genome-Encoded Superantigen Contributes to Lethality of Community-Associated MRSA Necrotizing Pneumonia
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A Wide Extent of Inter-Strain Diversity in Virulent and Vaccine Strains of Alphaherpesviruses
PLOS Pathogens: published October 13, 2011 | https://doi.org/10.1371/journal.ppat.1002282
Hepatitis C Virus Reveals a Novel Early Control in Acute Immune Response
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Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of the Mutualistic Root Symbiont Piriformospora indica
PLOS Pathogens: published October 13, 2011 | https://doi.org/10.1371/journal.ppat.1002290
Biochemical and Structural Insights into the Mechanisms of SARS Coronavirus RNA Ribose 2′-O-Methylation by nsp16/nsp10 Protein Complex
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The Role of Sialyl Glycan Recognition in Host Tissue Tropism of the Avian Parasite Eimeria tenella
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A Viral Nuclear Noncoding RNA Binds Re-localized Poly(A) Binding Protein and Is Required for Late KSHV Gene Expression
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The DEAD-box RNA Helicase DDX6 is Required for Efficient Encapsidation of a Retroviral Genome
PLOS Pathogens: published October 13, 2011 | https://doi.org/10.1371/journal.ppat.1002303
The Anti-Sigma Factor TcdC Modulates Hypervirulence in an Epidemic BI/NAP1/027 Clinical Isolate of Clostridium difficile
PLOS Pathogens: published October 13, 2011 | https://doi.org/10.1371/journal.ppat.1002317
Toll-8/Tollo Negatively Regulates Antimicrobial Response in the Drosophila Respiratory Epithelium
PLOS Pathogens: published October 13, 2011 | https://doi.org/10.1371/journal.ppat.1002319
Haemophilus influenzae Infection Drives IL-17-Mediated Neutrophilic Allergic Airways Disease
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002244
IRAK-2 Regulates IL-1-Mediated Pathogenic Th17 Cell Development in Helminthic Infection
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002272
Blood Feeding and Insulin-like Peptide 3 Stimulate Proliferation of Hemocytes in the Mosquito Aedes aegypti
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002274
The Herpes Simplex Virus-1 Transactivator Infected Cell Protein-4 Drives VEGF-A Dependent Neovascularization
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002278
Critical Roles for LIGHT and Its Receptors in Generating T Cell-Mediated Immunity during Leishmania donovani Infection
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002279
Evolutionarily Divergent, Unstable Filamentous Actin Is Essential for Gliding Motility in Apicomplexan Parasites
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002280
Noninfectious Retrovirus Particles Drive the Apobec3/Rfv3 Dependent Neutralizing Antibody Response
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002284
Chlamydia trachomatis Co-opts the FGF2 Signaling Pathway to Enhance Infection
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002285
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HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types
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Fumarate Reductase Activity Maintains an Energized Membrane in Anaerobic Mycobacterium tuberculosis
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002287
Homeostatic Proliferation Fails to Efficiently Reactivate HIV-1 Latently Infected Central Memory CD4+ T Cells
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002288
A Genetic Screen Reveals Arabidopsis Stomatal and/or Apoplastic Defenses against Pseudomonas syringae pv. tomato DC3000
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002291
The Anti-interferon Activity of Conserved Viral dUTPase ORF54 is Essential for an Effective MHV-68 Infection
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002292
Toll-like Receptor 7 Controls the Anti-Retroviral Germinal Center Response
PLOS Pathogens: published October 6, 2011 | https://doi.org/10.1371/journal.ppat.1002293
Sustained CD8+ T Cell Memory Inflation after Infection with a Single-Cycle Cytomegalovirus
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Drosophila melanogaster as an Animal Model for the Study of Pseudomonas aeruginosa Biofilm Infections In Vivo
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Mechanisms of Candida albicans Trafficking to the Brain
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