October 2007

Colorized scanning electron micrograph of African trypanosomes, which are transmitted by tsetse flies in Africa and cause human sleeping sickness. In the bloodstream, the trypanosomes evade the immune system by periodically switching their major surface protein. A trypanosome-encoded protease helps remove this protein when the trypanosomes are ingested by tsetse flies (See Grandgenett et al, e150.)

Image Credit: Image provided by Jared R. Helm and the University of Iowa Central Microscopy Research Facility.

Opinion

Pathogenesis, Virulence, and Infective Dose

Paul Schmid-Hempel, Steven A Frank

PLOS Pathogens: published October 26, 2007 | https://doi.org/10.1371/journal.ppat.0030147

Review

Surveillance of Arthropod Vector-Borne Infectious Diseases Using Remote Sensing Techniques: A Review

Satya Kalluri, Peter Gilruth, David Rogers, Martha Szczur

PLOS Pathogens: published October 26, 2007 | https://doi.org/10.1371/journal.ppat.0030116

Research Articles

Growth of H5N1 Influenza A Viruses in the Upper Respiratory Tracts of Mice

Masato Hatta, Yasuko Hatta, Jin Hyun Kim, Shinji Watanabe, Kyoko Shinya, Tung Nguyen, Phuong Song Lien, Quynh Mai Le, Yoshihiro Kawaoka

PLOS Pathogens: published October 5, 2007 | https://doi.org/10.1371/journal.ppat.0030133

A Virtual Look at Epstein–Barr Virus Infection: Biological Interpretations

Karen A Duca, Michael Shapiro, Edgar Delgado-Eckert, Vey Hadinoto, Abdul S Jarrah, Reinhard Laubenbacher, Kichol Lee, Katherine Luzuriaga, Nicholas F Polys, David A Thorley-Lawson

PLOS Pathogens: published October 19, 2007 | https://doi.org/10.1371/journal.ppat.0030137

A Single Mutation in the PB1-F2 of H5N1 (HK/97) and 1918 Influenza A Viruses Contributes to Increased Virulence

Gina M Conenello, Dmitriy Zamarin, Lucy A Perrone, Terrence Tumpey, Peter Palese

PLOS Pathogens: published October 5, 2007 | https://doi.org/10.1371/journal.ppat.0030141

A Viral Nanoparticle with Dual Function as an Anthrax Antitoxin and Vaccine

Darly J Manayani, Diane Thomas, Kelly A Dryden, Vijay Reddy, Marc E Siladi, John M Marlett, G. Jonah A Rainey, Michael E Pique, Heather M Scobie, Mark Yeager, John A. T Young, Marianne Manchester, Anette Schneemann

PLOS Pathogens: published October 5, 2007 | https://doi.org/10.1371/journal.ppat.0030142

Malaria Impairs T Cell Clustering and Immune Priming despite Normal Signal 1 from Dendritic Cells

Owain R Millington, Vivienne B Gibson, Catherine M Rush, Bernd H Zinselmeyer, R. Stephen Phillips, Paul Garside, James M Brewer

PLOS Pathogens: published October 12, 2007 | https://doi.org/10.1371/journal.ppat.0030143

Human CD4⁺ T Cell Epitopes from Vaccinia Virus Induced by Vaccination or Infection

J. Mauricio Calvo-Calle, Iwona Strug, Maria-Dorothea Nastke, Stephen P Baker, Lawrence J Stern

PLOS Pathogens: published October 12, 2007 | https://doi.org/10.1371/journal.ppat.0030144

HMBA Releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and Activates HIV Transcription

Xavier Contreras, Matjaz Barboric, Tina Lenasi, B. Matija Peterlin

PLOS Pathogens: published October 12, 2007 | https://doi.org/10.1371/journal.ppat.0030146

Genome Sequence of Babesia bovis and Comparative Analysis of Apicomplexan Hemoprotozoa

Kelly A Brayton, Audrey O. T Lau, David R Herndon, Linda Hannick, Lowell S Kappmeyer, Shawn J Berens, Shelby L Bidwell, Wendy C Brown, Jonathan Crabtree, Doug Fadrosh, Tamara Feldblum, Heather A Forberger, Brian J Haas, Jeanne M Howell, Hoda Khouri, Hean Koo, David J Mann, Junzo Norimine, Ian T Paulsen, Diana Radune, Qinghu Ren, Roger K Smith Jr., Carlos E Suarez, Owen White, Jennifer R Wortman, Donald P Knowles Jr., Terry F McElwain, Vishvanath M Nene

PLOS Pathogens: published October 19, 2007 | https://doi.org/10.1371/journal.ppat.0030148

Correction

Correction: Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression

Jason D Barbour, Uma Sriram, Stacy J Caillier, Jay A Levy, Frederick M Hecht, Jorge R Oksenberg

PLOS Pathogens: published October 26, 2007 | https://doi.org/10.1371/journal.ppat.0030154

Cover

African trypanosomes

Opinion

Pathogenesis, Virulence, and Infective Dose

Review

Surveillance of Arthropod Vector-Borne Infectious Diseases Using Remote Sensing Techniques: A Review

Research Articles

Growth of H5N1 Influenza A Viruses in the Upper Respiratory Tracts of Mice

A Virtual Look at Epstein–Barr Virus Infection: Biological Interpretations

A Single Mutation in the PB1-F2 of H5N1 (HK/97) and 1918 Influenza A Viruses Contributes to Increased Virulence

A Viral Nanoparticle with Dual Function as an Anthrax Antitoxin and Vaccine

Malaria Impairs T Cell Clustering and Immune Priming despite Normal Signal 1 from Dendritic Cells

Human CD4⁺ T Cell Epitopes from Vaccinia Virus Induced by Vaccination or Infection

HMBA Releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and Activates HIV Transcription

Genome Sequence of Babesia bovis and Comparative Analysis of Apicomplexan Hemoprotozoa

A Function for a Specific Zinc Metalloprotease of African Trypanosomes

Influenza Virus Transmission Is Dependent on Relative Humidity and Temperature

Target Cell APOBEC3C Can Induce Limited G-to-A Mutation in HIV-1

RNAi Screen in Drosophila Cells Reveals the Involvement of the Tom Complex in Chlamydia Infection

Evidence for Direct Involvement of the Capsid Protein in HIV Infection of Nondividing Cells

Contrasting Infection Strategies in Generalist and Specialist Wasp Parasitoids of Drosophila melanogaster

Small-Molecule Inhibition of HIV pre-mRNA Splicing as a Novel Antiretroviral Therapy to Overcome Drug Resistance

Correction

Correction: Synergy or Independence? Deciphering the Interaction of HLA Class I and NK Cell KIR Alleles in Early HIV-1 Disease Progression

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