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PLoS Pathogens Issue Image | Vol. 9(4) April 2013

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Immune regulation during helminth infections

Helminths are very successful at regulating host immune responses to evade rejection and as a consequence may also protect the host from certain autoimmune diseases. Clinical trials are underway to determine if reintroducing helminths to patients may be a viable therapeutic strategy. In a Pearls article, Girgis et al. review features of the immune response against helminths, focusing in particular on immune regulation. The picture shows Trichuris trichiura eggs inside a female worm from an infected individual.

Image Credit: Kimberley Evason, UCSF School of Medicine, Department of Pathology

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Immune regulation during helminth infections

Helminths are very successful at regulating host immune responses to evade rejection and as a consequence may also protect the host from certain autoimmune diseases. Clinical trials are underway to determine if reintroducing helminths to patients may be a viable therapeutic strategy. In a Pearls article, Girgis et al. review features of the immune response against helminths, focusing in particular on immune regulation. The picture shows Trichuris trichiura eggs inside a female worm from an infected individual.

Image Credit: Kimberley Evason, UCSF School of Medicine, Department of Pathology

https://doi.org/10.1371/image.ppat.v09.i04.g001