Figures
BrdU+ monocytes and macrophages in a simian immunodeficiency virus encephalitis (SIVE) lesion.
This confocal micrograph shows cells triple-labeled with antibodies against BrdU (red), SIVp28 (green), and CD68 (blue). BrdU+ cells (red) that were not infected were identified in a lesion of an animal with SIVE. Numerous CD68+ and SIVp28+ cells are seen in this lesion; few of the mature CD68+ macrophages are BrdU+. The majority of BrdU+ cells are nonproductively infected (see Burdo et al., doi:10.1371/journal.ppat.1000842).
Image Credit: Xavier Alvarez (Tulane National Primate Research Center, Tulane University).
Citation: (2010) PLoS Pathogens Issue Image | Vol. 6(4) April 2010. PLoS Pathog 6(4): ev06.i04. https://doi.org/10.1371/image.ppat.v06.i04
Published: April 29, 2010
Copyright: © 2010 Xavier Alvarez. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
This confocal micrograph shows cells triple-labeled with antibodies against BrdU (red), SIVp28 (green), and CD68 (blue). BrdU+ cells (red) that were not infected were identified in a lesion of an animal with SIVE. Numerous CD68+ and SIVp28+ cells are seen in this lesion; few of the mature CD68+ macrophages are BrdU+. The majority of BrdU+ cells are nonproductively infected (see Burdo et al., doi:10.1371/journal.ppat.1000842).
Image Credit: Xavier Alvarez (Tulane National Primate Research Center, Tulane University).