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Open Access
Peer-reviewed
Research Article
Hepatitis B Virus Infection and Immunopathogenesis in a Humanized Mouse Model: Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages
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Moses T. Bility ,
* E-mail: moses_bility@med.unc.edu (MTB); lsu@med.unc.edu (LS)
Affiliation Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Liang Cheng,
Affiliation Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Zheng Zhang,
Affiliation Center of Infectious Disease, Beijing 302 Hospital, Beijing, China
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Yan Luan,
Affiliations Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Department of Pathology, University of Chicago, Chicago, Illinois, United States of America
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Feng Li,
Affiliation Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Liqun Chi,
Affiliation Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Liguo Zhang,
Affiliation Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
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Zhengkun Tu,
Affiliations Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Department of Translational Medicine, Department of Surgery, Department of Medicine, the First Hospital, Jilin University, Changchun, Jilin, China
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Yanhang Gao,
Affiliation Department of Translational Medicine, Department of Surgery, Department of Medicine, the First Hospital, Jilin University, Changchun, Jilin, China
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Yangxin Fu,
Affiliations Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Department of Pathology, University of Chicago, Chicago, Illinois, United States of America
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Junqi Niu,
Affiliation Department of Translational Medicine, Department of Surgery, Department of Medicine, the First Hospital, Jilin University, Changchun, Jilin, China
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Fusheng Wang,
Affiliation Center of Infectious Disease, Beijing 302 Hospital, Beijing, China
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Lishan Su
* E-mail: moses_bility@med.unc.edu (MTB); lsu@med.unc.edu (LS)
Affiliations Lineberger Comprehensive Cancer Center, Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America, Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, Department of Translational Medicine, Department of Surgery, Department of Medicine, the First Hospital, Jilin University, Changchun, Jilin, China
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Hepatitis B Virus Infection and Immunopathogenesis in a Humanized Mouse Model: Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages
- Moses T. Bility,
- Liang Cheng,
- Zheng Zhang,
- Yan Luan,
- Feng Li,
- Liqun Chi,
- Liguo Zhang,
- Zhengkun Tu,
- Yanhang Gao,
- Yangxin Fu
- Published: March 20, 2014
- https://doi.org/10.1371/journal.ppat.1004032