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De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans

  • Carl A. Morrow,

    Affiliations Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

  • Eugene Valkov,

    Affiliations School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia, MRC Laboratory of Molecular Biology, Cambridge, United Kingdom, Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia

  • Anna Stamp,

    Affiliation School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

  • Eve W. L. Chow,

    Affiliations Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

  • I. Russel Lee,

    Affiliations Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

  • Ania Wronski,

    Affiliation School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

  • Simon J. Williams,

    Affiliations Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

  • Justine M. Hill,

    Affiliations School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia, Centre for Advanced Imaging, University of Queensland, Brisbane, Queensland, Australia

  • Julianne T. Djordjevic,

    Affiliation Centre for Infectious Diseases and Microbiology, Westmead Millennium Institute, University of Sydney at Westmead Hospital, Sydney, New South Wales, Australia

  • Ulrike Kappler,

    Affiliations Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

  • Bostjan Kobe,

    Affiliations Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia, Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia

  • James A. Fraser

    jafraser@uq.edu.au

    Affiliations Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, Queensland, Australia, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

De novo GTP Biosynthesis Is Critical for Virulence of the Fungal Pathogen Cryptococcus neoformans

  • Carl A. Morrow, 
  • Eugene Valkov, 
  • Anna Stamp, 
  • Eve W. L. Chow, 
  • I. Russel Lee, 
  • Ania Wronski, 
  • Simon J. Williams, 
  • Justine M. Hill, 
  • Julianne T. Djordjevic, 
  • Ulrike Kappler
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