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Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation

  • Kevin N. Couper ,

    kevin.couper@lshtm.ac.uk (KNC); brian.desouza@lshtm.ac.uk (JBdS)

    Affiliation Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  • Tom Barnes,

    Affiliations Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Department of Immunology and Molecular Pathology, University College London Medical School, London, United Kingdom

  • Julius C. R. Hafalla,

    Affiliation Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  • Valery Combes,

    Affiliation Department of Pathology, University of Sydney, Camperdown, New South Wales, Australia

  • Bernhard Ryffel,

    Affiliation Molecular Immunology and Embryology, University of Orleans and Centre National de la Recherche Scientifique, Orleans, France

  • Thomas Secher,

    Affiliation Molecular Immunology and Embryology, University of Orleans and Centre National de la Recherche Scientifique, Orleans, France

  • Georges E. Grau,

    Affiliation Department of Pathology, University of Sydney, Camperdown, New South Wales, Australia

  • Eleanor M. Riley,

    Affiliation Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom

  • J. Brian de Souza

    kevin.couper@lshtm.ac.uk (KNC); brian.desouza@lshtm.ac.uk (JBdS)

    Affiliations Immunology Unit, Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom, Department of Immunology and Molecular Pathology, University College London Medical School, London, United Kingdom

Parasite-Derived Plasma Microparticles Contribute Significantly to Malaria Infection-Induced Inflammation through Potent Macrophage Stimulation

  • Kevin N. Couper, 
  • Tom Barnes, 
  • Julius C. R. Hafalla, 
  • Valery Combes, 
  • Bernhard Ryffel, 
  • Thomas Secher, 
  • Georges E. Grau, 
  • Eleanor M. Riley, 
  • J. Brian de Souza
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